Acta Scientific Veterinary Sciences (ISSN: 2582-3183)

Research Article Volume 6 Issue 4

Prevalence and Pathology of Feline Panleukopenia in Domestic Cats

Kadam MB1, Sawale GK1*, Gandge RS2, Ingle SA3, Rohi RR4 and Meshram PV1

1Department of Veterinary Pathology, Mumbai Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, Maharashtra, India
2Department of Veterinary Microbiology, Mumbai Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, Maharashtra, India
3Department of Animal Biotechnology, Mumbai Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, Maharashtra, India
4TVCC, MVC, Goregaon, Mumbai Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, Maharashtra, India

*Corresponding Author: Sawale GK, Department of Veterinary Pathology, Mumbai Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, Maharashtra, India.

Received: February 16, 2024Published: March 15, 2024

Abstract

Prevalence and pathology of feline panleukopenia was conducted in cats of Mumbai region from January 2020 to January 2021 and prevalence was found to be 70% (35/50). Age wise study revealed higher incidence of FPL in the age group of 0- 6 months (56%), followed by 6-12 months (8%) and lowest in one year and above group (6%). Non- descript cats/kittens (85.72%) were found to be affected at a higher percentage than pure breed (Persian) cats (14.28%). The higher percentage of female cats (65.71%) were affected by FPL than males (34.29%) cats. Necropsy examination of cat died due to FPL showed catarrhal exudation with hyperaemia, haemorrhages in stomach and intestinal mucosa, enlarged mesenteric lymph nodes and slightly pale bone marrow. Lung and liver were congested. Microscopically, section of small intestine showed coagulative necrosis, dilatation of crypt containing mucus and necrotic debris and denudation of villi and proliferative changes in submucosa. Infiltration of inflammatory cells like polymorphs, lymphocytes and basophilic intranuclear inclusions in intestine and stomach as well as bacterial colonies in stomach were observed. Lymph nodes and spleen showed lymphoid cell depletion whereas lung showed acute interstitial pneumonia. For diagnosis of FPL, SNAP test could able to detect 58% (29/50) of sample while PCR detected 70% (35/50) and PCR appeared to be more sensitive than SNAP test.

Keywords: Feline Panleukopenia; Cats; Pathology; Prevalence; PCR and SNAP test

References

  1. Vegad JL and Katiyar AK. “Textbook of Veterinary Special Pathology, 1ST Edition”. CBS (Publisher) Pvt, Ltd. Delhi (2016).
  2. Richard AS. “Feline Panleukopenia In MSD Veterinary manual” (2020).
  3. Parrish CR., et al. “Characterization of antigenic variation among mink enteritis virus isolates. American Journal of Veterinary Research 45 (1984): 2591-2599.
  4. Barrs VR. “Feline panleukopenia: a re-emergent disease”. Veterinary Clinics: Small Animal Practice 49 (2019): 651-670.
  5. Mochizuki M., et al. “Isolation of canine parvovirus from a cat manifesting clinical signs of feline panleukopenia”. Journal of Clinical Microbiology 34 (1996): 2101-2105.
  6. Bayati HAMA. “Detection of feline parvovirus (FPV) from cats infected with enteritis using rapid test and polymerase chain reaction in Iraq. Kufa”. Journal for Veterinary Medical Sciences 7 (2016): 61-70.
  7. Raheena Koulath P., et al. “Comparison of different diagnostic test to detect feline panleukopenia virus among cats in Kerala, India”. Indian Journal of Animal Research2 (2017): 347-349.
  8. Awad RA., et al. “Epidemiology and diagnosis of feline panleukopenia virus in Egypt: Clinical and molecular diagnosis in cats”. Veterinary World 11 (2018): 578-584.
  9. Bakde RA. “Clinico-epidemiological studies and molecular diagnosis of feline panleukopenia in cats” (PG dissertation, College of Veterinary and Animal Sciences, Pookode Wayanad) (2019).
  10. Abd-Eldaim M., et al. “Detection of feline panleukopenia virus using a commercial ELISA for canine parvovirus”. Veterinary Therapeutics 10 (2009): E1-6.
  11. Islam M., et al. “Antigenic detection of feline panleukopenia virus in local breed cats at Tangail District in Bangladesh”. International Journal of Biological Research 2 (2010): 25-28.
  12. Bukar-Kolo YM., et al. “Prevalence of feline panleukopenia virus in pet and stray cats and associated risk factors in Maiduguri, Nigeria”. Alexandria Journal for Veterinary Sciences (2018). 59.
  13. Kim SG., et al. “Prevalence of feline panleukopenia virus in stray and household cats in Seoul, Korea”. Journal of Veterinary Clinics 30 (2013): 333-338.
  14. Mosallanejad B., et al. “Antigenic detection of Feline Panleukopenia virus (FPV) in diarrhoeic companion cats in Ahvaz area”. Iranian Journal of Veterinary Research3 (2009): 289-293.
  15. Kruse BD., et al. “Prognostic factors in cats with feline panleukopenia”. Journal of Veterinary Internal Medicine 24 (2010): 1271-1276.
  16. Castro NB., et al. “Pathologic and immunohistochemical findings of domestic cats with feline panleukopenia”. Pesquisa Veterinária Brasileira 34 (2014): 770-775.
  17. Zenad MM and Radhy AM. “Clinical, serological and antigenic study of feline panleukopenia virus in cats in Baghdad, Iraq”. Iraqi Journal of Veterinary Sciences 34 (2020): 435-439.
  18. Citarova A and Mojzisová J. “The effect of the sex on the presence of feline panleukopenia”. Journal of Veterinary Medical Research 7 (2020): 1182.
  19. Jones TC., et al. “Parvoviridae” In: Veterinary Pathology, 6th Williams and Wilkins (1997): 257-261.
  20. Lane EP., et al. “Feline panleukopaenia virus in captive non-domestic felids in South Africa”. Onderstepoort Journal of Veterinary Research 83 (2016): 1-8.
  21. Carison IH., et al. “Feline Panleukopenia: I. Pathogenesis in Germfree and Specific Pathogen-Free Cats”. Veterinary Patholology 14 (1977): 79-88.
  22. Carlson JH., et al. “Feline Panleukopenia: III. Development of lesions in the lymphoid Tissues”. Veterinary Pathology 15 (1978): 383-392.
  23. Boes KM and Durham AC. “Bone marrow, blood cells, and the lymphoid/lymphatic system”. Pathologic Basis of Veterinary Disease (2017): 724.

Citation

Citation: Sawale GK., et al. “Prevalence and Pathology of Feline Panleukopenia in Domestic Cats". Acta Scientific Veterinary Sciences 6.4 (2024): 40-47.

Copyright

Copyright: © 2024 Sawale GK., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
Impact Factor1.008

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is April 30th, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue".
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US