Reshma Sinha*, Babita Rana and Deepa Sharma

Department of Animal Sciences, Central University of Himachal Pradesh, India

*Corresponding Author: Reshma Sinha, Department of Animal Sciences, Central University of Himachal Pradesh, India.

Received: January 29, 2024Published: February 29, 2024

Abstract

Introduction: Cancer ranks high amongst the topmost causes of mortality globally. Several factors such as stressful living, pollution, irregular habitual activities, UV exposures and ionizing radiations, toxic drugs, and genetic alterations are contributing to enhanced incidences of cancer. Surgery, chemotherapy, and radiation therapy are conventional cancer therapies that often cause serious side effects on human health. Scientists are moving towards alternatives and exploring natural remedies such as plant extracts and natural products for both treatment and prevention.

Methodology: For the present article, research, review and official documents were referred which followed the keywords- endemic, herbal, extract, anti-cancer and Himalayas.

Results: The Himalayan region is the hub of endemic medicinal floras, which can be utilized in the curing of multiple ailments and disorders including cancer without causing serious side effects. In the current review article, we have documented 8 endemic medic herbs namely Bergenia ciliata, Cedrus deodara, Gentiana kurroo, Podophyllum hexandrum, Osmunda regalis, Nardostachys jatamansi, Coptis teeta, and Saussurea costus. Studies reporting the cytotoxic efficacies of extracts of these floras have shown significant results in the suppression of cancer cells in various animal models through DNA damage and activation of apoptosis-inducing enzymes. The review will provide basic information to the researchers interested in developing newer, safe, and standard herbal drugs to prevent and cure cancer.

Conclusion: Further greater extensive researches are required to document the unique medicinal floras of the Himalayan region and to explore their hidden potentials, bioactive compounds, and mechanism of anticancer activities to develop herbal drugs.

Keywords: Anticancer; Cytotoxicity; Endemic plants; Himalayas; Phytochemicals

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Citation

Citation: Reshma Sinha., et al. “A Review on Anti-Cancer Properties of Medicinal Plants Endemic to the Himalayas".Acta Scientific Veterinary Sciences 6.3 (2024): 119-129.

Copyright

Copyright: © 2024 Reshma Sinha., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.