Acta Scientific Veterinary Sciences (ISSN: 2582-3183)

Research Article Volume 6 Issue 1

Antidiarrhoeal Efficacy of Homeopathic Preparation Echinacea Angustifolia Against Naturally Occurring Neonatal Calve Diarrhoea

Mondal Debabrata1*, Raguvaran Raja2, Dosar Shivangi3, Dixit Shivendra Kumar1, Narula Ritika Hassija4 and Khurana Anil5*

1Pr. Scientist, Division of Medicine, IVRI, UP, India
2Scientist (SS) Division of Medicine, IVRI, UP, India
3JRF, Division of Medicine, IVRI, UP, India
4Scientist, CCRH, Delhi India
5Director, CCRH, Delhi India

*Corresponding Author: Mondal Debabrata, Scientist (SS) Division of Medicine, IVRI, UP, India.

Received: October 31, 2023 Published: December 18, 2023

Abstract

Background and Objective: Need based clinical research with homeopathic medicine as compared to conventional allopathic treatment is the best bet option to overcome sole dependency on allopath.

Method: Present study was envisaged to evaluate therapeutic potential of homeopathic formulation Echinacea angustifolia (Ea) in different potencies viz, (θ, 30C and 200C) against naturally occurring neonatal calf diarrhoea to overcome the detrimental effect of indiscriminate use of antibiotics in dairy herds. Randomised controlled trial performed against naturally occurring clinical cases of neonatal diarrhoea. Therapeutic efficacy was assessed based on resolution of clinical signs and improvement in hematobiochemical and oxidative stress indices.

Results: Clinical recovery was earlier in E. angustifolia treated group whereas it was delayed in other groups including standard antibiotic treated groups in this study.

Conclusion: Echinacea angustifolia 200C may effectively treat neonatal calf diarrhoea under standard managemental condition and may reduce indiscriminate usage of antibiotic in livestock industry.

Keywords: Diarrhoea; Echinacea Angustifolia; Homeopathy; Neonatal

References

  1. Bartels CJ., et al. “Prevalence, prediction and risk factors of enteropathogens in normal and non-normal faeces of young Dutch dairy calves”. Preventive Veterinary Medicine2-3 (2010): 162-169.
  2. Windeyer MC., et al. “Factors associated with morbidity, mortality, and growth of dairy heifer calves up to 3 months of age”. Preventive Veterinary Medicine 2 (2014): 231-240.
  3. Meganck Vanessa., et al. “Evaluation of a protocol to reduce the incidence of neonatal calf diarrhoea on dairy herds”. Preventive Veterinary Medicine1 (2015): 64-70.
  4. Aidara-Kane Awa., et al. “World Health Organization (WHO) guidelines on use of medically important antimicrobials in food-producing animals”. Antimicrobial Resistance and Infection Control7 (2018): 1-8.
  5. Fortuoso Bruno F., et al. “Homeopathic treatment as an alternative prophylactic to minimize bacterial infection and prevent neonatal diarrhea in calves”. Microbial Pathogenesis114 (2018): 95-98.
  6. Cheng Yan., et al. “Changes of intestinal oxidative stress, inflammation, and gene expression in neonatal diarrhoea kids”. Frontiers in Veterinary Science8 (2021): 598691.
  7. Birben Esra., et al. “Oxidative stress and antioxidant defense”. World Allergy Organization Journal5 (2012): 9-19.
  8. Woelkart K., et al. “Bioavailability and pharmacokinetics of Echinacea purpurea preparations and their interaction with the immune system”. International Journal of Clinical Pharmacology and Therapeutics9 (2006).
  9. JK Aronson “(in Meyler's Side Effects of Drugs, 2016). Echinacea Angustifolia: Text book of natural medicine (5th Edition) (2020).
  10. Yamada Koji., et al. “A comparison of the immunostimulatory effects of the medicinal herbs Echinacea, Ashwagandha and Brahmi”. Journal of Ethnopharmacology1 (2011): 231-235.
  11. Wani SA., et al. “Diarrhoeagenic Escherichia coli and salmonellae in calves and lambs in Kashmir: absence, prevalence and antibiogram”. Revue Scientifique et Technique 3 (2013): 833-840.
  12. Galland John C., et al. “Prevalence, antibiotic susceptibility, and diversity of Escherichia coli O157: H7 isolates from a longitudinal study of beef cattle feedlots”. Applied and Environmental Microbiology4 (2001): 1619-1627.
  13. Khawaskar Damini P., et al. “Pathotyping and antimicrobial susceptibility testing of Escherichia coli isolates from neonatal calves”. Veterinary Research Communications2 (2022): 353-362.
  14. Jacobs Jennifer., et al. “Treatment of acute childhood diarrhea with homeopathic medicine: a randomized clinical trial in Nicaragua”. Pediatrics5 (1994): 719-725.
  15. Hodges Kim and Ravinder Gill. "Infectious diarrhea: Cellular and molecular mechanisms”. Gut Microbes1 (2010): 4-21.
  16. Bokelmann JM. "Echinacea (Echinacea purpurea, Echinacea angustifolia)”. Medicinal Herbs in Primary Care. Elsevier (2021): 317-322.
  17. Brand-Williams., et al. “Use of a free radical method to evaluate antioxidant activity”. LWT-Food Science and Technology1 (1995): 25-30.
  18. Benzie Iris FF and John J Strain. "The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay”. Analytical Biochemistry1 (1996): 70-76.
  19. , et al. “Species specific PCR based detection of Escherichia coli from Indian foods”. 3 Biotech7 (2017): 1-5.

Citation

Citation: Mondal Debabrata., et al. “Antidiarrhoeal Efficacy of Homeopathic Preparation Echinacea Angustifolia Against Naturally Occurring Neonatal Calve Diarrhoea".Acta Scientific Veterinary Sciences 6.1 (2024): 80-88.

Copyright

Copyright: © 2024 Mondal Debabrata., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
Impact Factor1.008

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 30, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US