SS Devi¹*, JG Ajith², B Dhanush Krishna¹, KS Prasanna¹, G Radhika³ and KD John Martin⁴

¹Assistant Professor, Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala Veterinary and Animal Sciences University, Kerala, India
²Professor and Head, Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala Veterinary and Animal Sciences University, Kerala, India
³Professor, Department of Animal Breeding and Genetics, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala Veterinary and Animal Sciences University, Kerala, India
⁴Professor and Head, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala Veterinary and Animal Sciences University, Kerala, India

*Corresponding Author: SS Devi, Assistant Professor, Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala Veterinary and Animal Sciences University, Kerala, India.

Received: July 20, 2023; Published: August 29, 2023

Abstract

The study was conducted in samples of mammary carcinomas obtained from dogs that were brought to University Veterinary Hospitals, Mannuthy and Kokkalai during a study period of one year. The study employed cytological grading system proposed by Robinson., et al. (1994) in human breast carcinomas (HBCs) with necessary modifications. Histopathological grading was done according to the inputs by Clemente., et al. (2010) which is a modification of the Nottingham system of malignancy grading in HBCs. The grades obtained for carcinomas in both the evaluations were compared and absolute concordance rate as well as separate concordance rates for each grade of carcinoma was assessed. The results revealed satisfactory concordance (87.5 per cent) and a significant positive correlation between the two methods of grading mammary carcinomas in canines. Further, the sensitivity and specificity of cytological grading was assessed with respect to histological grading and the results revealed that cytological grading was 100 per cent specific in case of grade III carcinomas and 100 per cent sensitive for grade I carcinomas. The study concluded that cytological evaluation of fine needle aspirate from canine mammary carcinomas can give the clinician firsthand information regarding the selection of treatment methods to be adopted before surgical resection.

Keywords: Canine Mammary Carcinomas; Cytology; Concordance; Grading

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Citation

Citation: SS Devi., et al. “Comparative Analysis of Cytological and Histological Grading Techniques in Canine Mammary Carcinomas".Acta Scientific Veterinary Sciences 5.9 (2023): 114-120.

Copyright

Copyright: © 2023 SS Devi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.