*Corresponding Author: Aditya Sharma, Assistant Professor, Department of Veterinary Pathology, KCVAS, Amritsar, Punjab, India.

Received: May 22, 2023; Published: May 30, 2023

Abstract

Atherosclerosis is a chronic progressive disease caused by vascular injury, and is induced by the interaction of various inflammatory cells and mediators. The Kruppel-like factor 4 (KLF4) is an important transcription factor that has a role in cell growth, differentiation, proliferation, and regulation of cardiovascular disease. It is gained interest of scientist as KLF4, in particular, plays an important role in the pathogenesis of atherosclerosis.KLF4 may be an important “molecular switch” and is being used as biomarker and therapeutic targetin atherosclerosis and vascular disease.

Keywords: Kruppel Like Factor; KLF4; Atherosclerosis; Cardiovascular Disease

References

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Citation

Citation: Sheikh Uzma Farooq and Aditya Sharma. “Kruppel Like Factor and Endothelial Dysfunctions". Acta Scientific Veterinary Sciences 5.6 (2023): 80-82.

Copyright

Copyright: © 2023 Sheikh Uzma Farooq and Aditya Sharma. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.