Surendra Upadhyay¹, Saumya Jaiswal¹, Tanya Malik¹, Vikas Jaiswal², NN Mohanty³, Vikas Gupta³, Anu Rahal⁴ and Amit Kumar1

¹Division of Animal Biotechnology, College of Biotechnology, SVPUAT, Meerut, India
²Department of Veterinary Pathology, College of Veterinary Sciences, SVPUAT, Meerut, India
³CCS- National Institute of Animal Health, Baghpat, India
⁴Division of Animal Health, ICAR-CIRG, Mathura, India

*Corresponding Author: Amit Kumar, Division of Animal Biotechnology, College of Biotechnology, SVPUAT, Meerut, India.

Received: April 04, 2023; Published: April 18, 2023

Abstract

Context: Lumpy skin disease, a transboundary disease recently spread across the India during 2022-2023 and caused unexpected mortality in the range of 2-10% in different states. It imposed a severe economic stress on the livestock based rural economy and adversely affected the export of animal based products. Government of India tried to prevent it by vaccinating more than 87 million animals with existing Goat pox vaccine. However, there are reports of infection in spite of vaccination. These might be because of variation of strain prevalent in particular state.

Objective: It is imperative to study the virus involved in the infection in particular state due to climatic and geographical variation. With this objective, the present study involved the molecular characterization and phylogeny analysis of LSD virus prevalent in Uttar Pradesh to ascertain any variation in virus.

Results: Samples collected from the clinical cases revealed the presence of LSD virus with WAHO recommended PCR based amplification. The further validation of the virus with amplification of ORF011 encoding G-protein-coupled receptors (GPCRs) led to phylogeny study of the virus.

Conclusions: The virus of UP aligned with other reported viruses of country and also showed highest resemblance with the reported viruses of the neighbouring countries like Myanmar, Nepal, Bangladesh and china. Keywords: Lumpy

Keywords: Lumpy Skin Disease Virus; Phylogeny; Cattle; Uttar Pradesh

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Citation

Citation: Amit Kumar., et al. “Molecular Characterization of Emerging Lumpy Skin Disease Virus in Western Uttar Pradesh, India". Acta Scientific Veterinary Sciences 5.5 (2023): 28-32.

Copyright

Copyright: © 2023 Amit Kumar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.