Serkan Ali AKARSU and Ali Doğan ÖMÜR*

Atatürk University, Faculty of Veterinary Medicine, Department of Reproduction and Artificial Insemination, Erzurum, Turkey

*Corresponding Author: Ali Doğan ÖMÜR, Atatürk University, Faculty of Veterinary Medicine, Department of Reproduction and Artificial Insemination, Erzurum, Turkey.

Received: February 13, 2023; Published: March 16, 2023

Abstract

Diabetes is a disease that develops when the secretory gland called the pancreas in the body does not produce enough insulin hormone or the insulin hormone it produces cannot be used effectively. Diabetes brings the following problems: eye problems, foot wounds, kidney disorders, cardiovascular disorders, susceptibility to infections, sexual problems. The information given below has been compiled to highlight the relationship of diabetes with reproductive parameters.

Keywords: Diabetes Mellitus; Sperm Cell; Oxidative Stress; Reproduction; Testis

References

1. Aitken RJ., et al. “Oxidative stress in the male germ line and its role in the aetiology of male infertility and genetic disease”. Reproductive Biomedicine Online1 (2003): 65-70.
2. Alves MG., et al. “Diabetes, insulin-mediated glucose metabolism and Sertoli/blood-testis barrier function”. Tissue Barriers2 (2013): e23992.
3. Amaral S., et al. “Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes”. Theriogenology66.9 (2006): 2056-2067.
4. Cameron DF., et al. “Sustained hyperglycemia results in testicular dysfunction and reduced fertility potential in BBWOR diabetic rats”. American Journal of Physiology-Endocrinology And Metabolism6 (1990): E881-E889.
5. Dias TR., et al. “Sperm glucose transport and metabolism in diabetic individuals”. Molecular and Cellular Endocrinology1-2 (2014): 37-45.
6. Handelsman DJ. “Hypothalamic-pituitary gonadal dysfunction in renal failure, dialysis and renal transplantation”. Endocrine Reviews 2 (1985): 151-182.
7. Hsueh WA., et al. “Insulin resistance and the endothelium”. The American Journal of Medicine117.2 (2004): 109-117.
8. Khaki A., et al. “Beneficial effects of quercetin on sperm parameters in streptozotocin‐induced diabetic male rats”. Phytotherapy Research9 (2010): 1285-1291.
9. Lebovitz HE and Banerji MA. “Treatment of insulin resistance in diabetes mellitus”. European Journal of Pharmacology1-3 (2004): 135-146.
10. Lee M., et al. “Diabetes mellitus and echocardiographic left ventricular function in free-living elderly men and women: The Cardiovascular Health Study”. American Heart Journal133.1 (1997): 36-43.
11. Navarro‐Casado L., et al. “Effect of experimental diabetes and STZ on male fertility capacity. Study in rats”. Journal of Andrology 6 (2010): 584-592.
12. Niven MJ., et al. “A study of spermatozoal motility in type 1 diabetes mellitus”. Diabetic Medicine12.10 (1995): 921-924.
13. Oehninger S., et al. “Factors affecting fertilization: endometrial placental protein 14 reduces the capacity of human spermatozoa to bind to the human zona pellucida”. Fertility and Sterility2 (1995): 377-383.
14. Pınar R., et al. “Quality of life and diabetes mellitus”. Turkish Journal of Endocrinology and Metabolism2.3 (1998):135-143.
15. Rama Raju GA., et al. “Noninsulin‐dependent diabetes mellitus: effects on sperm morphological and functional characteristics, nuclear DNA integrity and outcome of assisted reproductive technique”. Andrologia44 (2012): 490-498.
16. Roessner C., et al. “Sperm apoptosis signalling in diabetic men”. Reproductive biomedicine online 3 (2012):292-299.
17. Scarano WR, et al. “Sexual behaviour, sperm quantity and quality after short-term streptozotocin-induced hyperglycaemia in rats”. International Journal of Andrology 29 (2006):482-488. 
18. Sexton WJ and Jarow JP. “Effect of diabetes mellitus upon male reproductive function”. Urology 49.4 (1997): 508-513.
19. Sikka SC. “Relative impact of oxidative stress on male reproductive function”. Current Medicinal Chemistry 7 (2001): 851-862.
20. Vignon F., et al. “Comparative study of semen in diabetic and healthy men”. Diabete and Metabolisme 3 (1991): 350-354.

Citation

Citation: Serkan Ali AKARSU and Ali Doğan ÖMÜR. “Effects of Diabetes on the Male Genital System".Acta Scientific Veterinary Sciences 5.4 (2023): 30-32.

Copyright

Copyright: © 2023 Serkan Ali AKARSU and Ali Doğan ÖMÜR. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.