Baharak Akhtardanesh*, Dariush Vosough, Reza Kheirandish and Seyed AmirAbbas Razavi Parizi

Department of Clinical Sciences, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Iran

*Corresponding Author: Baharak Akhtardanesh, Professor of Small Animal Internal Medicine, Department of Clinical Sciences, School of Veterinary Medicine, Shahid Bahonar University of Kerman, Iran.

Received: January 06, 2023; Published: February 07, 2023

Abstract

Squamous cell carcinoma (SCC) is one of the most common malignant skin tumors in cats. A two years old male unowned domestic short hair cat was referred by an animal rescue volunteer with the history o severe lesions on the nasal planum, and mucopurulent nasal discharge. In physical examination, ulcers involved the whole nasal planum, eventually leading to loss of the rostral nasal cartilage and central upper lip but gingivostomatitis, and oral ulcer was not detected. Surprisingly anodontia of the permanent teeth was also detected in oral examination. Cytological examination of lesions revealed sparse cocci, many neutrophils and erythrocytes, and paraneoplastic (actinic) changes. Fine-needle aspiration of the submanibular lymph node showed no metastasis. The complete blood cells test (CBC) showed mild leukocytosis and anemia but no abnormality was detected in the biochemical survey. Skull Radiograph showed no evidence of teeth or unerupted teeth from the mandible and maxilla and severe bilateral nasal concha turbinate destruction. In thoracic and abdominal radiographs, there was no sign of metastasis. Biopsy specimens were collected under general anesthesia and revealed an irregularly hyperplastic epidermis, keratinocytes containing large vesicular nucleus and nucleolus with mild Pleomorphism and high mitotic index confirming the occurrence of SCC tumor. Unfortunately, this case was referred with severe destruction in ventral and dorsal nasal concha and cranial ethemotourbinates, facial deformity and osteolysis. Thus the cat was euthanized. Early diagnosis of SCC is paramount for prompt therapeutic intervention, which may result in long-term control or cure for affected patients.

Keywords: Squamous Cell Carcinoma; Cat; Histopathology; Andontia

References

1. Bilgic O., et al. “Feline Oral Squamous Cell Carcinoma: Clinical Manifestations and Literature Review”. Journal of Veterinary Dentistry1. (2015): 30-40.
2. Gasymova E., et al. “Retrospective Clinical Study on Outcome in Cats with Nasal Planum Squamous Cell Carcinoma Treated with an Accelerated Radiation Protocol”. BMC Veterinary Research1 (2017): 1-8.
3. Goodfellow M., et al. “A Retrospective Study of 90Strontium Plesiotherapy for Feline Squamous Cell Carcinoma of the Nasal Planum”. Journal of Feline Medicine and Surgery3 (2006): 169-176.
4. Helton R., et al. “Small Animal Dermatology”. Blackwell's Five-Minute Veterinary Consult Clinical Companion, Third edition, (2018): 672-690.
5. Meuten DJ. “Tumours in domestic animals”. Fifth edition, College of Veterinary Medicine, North Carolina State University, Raleigh (2017) USA: 97-99.
6. Layne EA and Graham M. “Cutaneous Squamous Cell Carcinoma Manifesting as Follicular Isthmus Cysts in a Cat”. Journal of Feline Medicine and Surgery Open Reports1 (2016): 5.
7. Miller Jr., et al. “Muller and Kirk's Small Animal Dermatology”. Elsevier. 7^th edition, (2013): 779-782.
8. Morris J and Dobson J. “Small Animal Oncology, Locoregional Tumor Therapy Head and Neck”. Cambridge Veterinary School (2001): 56-58.
9. Munday JS., et al. “Detection of Two Different Papillomaviruses within a Feline Cutaneous Squamous Cell Carcinoma: Case Report and Review of the Literature”. New Zealand Veterinary Journal4 (2009): 248-251.
10. Gasymova E., et al. Retrospective clinical study on outcome in cats with nasal planum squamous cell carcinoma treated with an accelerated radiation protocol”. BMC Veterinary Research1 (2017): 86.
11. Greene FL., et al. “AJCC cancer staging manual”. 6^th Springer; Chicago: (2002). Carcinoma of the skin (excluding eyelid, vulva, and penis).
12. Lana SE., et al. “Feline cutaneous squamous cell carcinoma of the nasal planum and the pinnae: 61 cases”. JAAHA4 (1997): 329-332.
13. Murphy S. “Cutaneous Squamous Cell Carcinoma in the Cat: Current Understanding and Treatment Approaches”. Journal of Feline Medicine and Surgery 15 5 (2013): 401-407.
14. Tozon N., et al. “Electrochemotherapy with Intravenous Bleomycin Injection: An Observational Study in Superficial Squamous Cell Carcinoma in Cats”. Journal of Feline Medicine and Surgery 16,4 (2014): 291-299.

Citation

Citation: Baharak Akhtardanesh. “A Giant Squamous Cell Carcinoma in an Andontic Domestic Shorthair Cat".Acta Scientific Veterinary Sciences 5.3 (2023): 17-20.

Copyright

Copyright: © 2023 Baharak Akhtardanesh. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.