Maharramov Saleh Heydar*

Department of Zoology, Nakhichevan State University, Nakhichevan

*Corresponding Author: Maharramov Saleh Heydar, Department of Zoology, Nakhichevan State University, Nakhichevan.

Received: November 10, 2022; Published: November 23, 2022

Abstract

In this study the embryotropic effect of Wormwood (Artemisia absinthium L.) - Rue (Peganum harmala L.) mixture, a mixture with strong antihelmentic affect, on pregnant rats was investigated. The study involved a total of 60 female rats; 30 in treatment group and 30 in control group. An equal combination of wormwood and rue was boiled to obtain the extract and this extract was orally given to the treatment group at the stage of implantation (Group I, n = 10), organogenesis (Group II, n = 10) and fetogenesis (Group III, n = 10) at the dose of 30g/kg body weight, daily for 2 days. Pregnancy and fetal development were monitored and differences determined were compared to the control group where similar grouping was made. Animals were euthanized at the last stage of gestation (21st day) and fetuses of the two groups were compared. Implantation, locality of re-absorption, number of live and death embryos, size and weight of embryos and placenta in treatment group were not different when compared to control group (P ≥ 0.05). Additionally no path-anatomical changes in internal organs of the fetuses were noted. This investigation concluded that the worm-wood-rue mixture had no embryotic effect in rats.

Keywords:Embryotrop; Vormwood; Rue; Toxicology

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Citation

Citation: Maharramov Saleh Heydar. “Investigation on Embryotropic Effect of Antihelmentic Plants ". Acta Scientific Veterinary Sciences 4.12 (2022): 149-153.

Copyright

Copyright: © 2022 Maharramov Saleh Heydar. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.