Aditya Sharma¹*, Sheikh Uzma Farooq² and Varun Khajuria³

¹Department of Veterinary Pathology, Khalsa College of Veterinary Sciences, Amritsar, India
²Department of Veterinary Pharmacology and Toxicology, Khalsa College of Veterinary Sciences, Amritsar, India
³Department of Veterinary Parasitology, Khalsa College of Veterinary Sciences, Amritsar, India

*Corresponding Author: Aditya Sharma, Assistant Professor, Department of Veterinary Pathology, KCVAS Amritsar, India.

Received: November 01, 2022; Published: November 02, 2022

Abstract

Lymphocytic choriomeningitis virus (LCMV) is an arena virus which causes nervous disorders in human beings as well as in mice and hamsters. Mice and hamsters are principal reservoir host of the virus and cover a large geographic area. They infect large number of human population especially during late autumn and early winter due to increase human-mouse contact. It is characterized by aseptic meningitis, encephalitis or meningoencephalitis and infected individual have abnormally high levels of lymphocytes during infection. The pathogenecity is determined by whether the virus is acquired postnatally by children or adults or prenatally. The clinical manifestations in postnatal infection are aseptic meningitis with good prognosis. However prenatally, LCMV can lead to infection in the fetal nervous system and retina, where it causes substantial injury with permanent dysfunctioning and grave prognosis.

Keywords: Lymphocytic Choriomeningitis Virus; Aseptic Meningitis; Encephalitis; Meningoencephalitis

References

1. Barton LL and Mets MB. “Congenital lymphocytic choriomeningitis virus infection: decade of rediscovery”. Clinical Infectious Diseases 33 (2001): 370-374.
2. Larsen PD., et al. “Hydrocephalus complicating lymphocytic choriomeningitis virus infection”. The Pediatric Infectious Disease Journal 12 (1993): 528-531.
3. Buchmeier MJ., et al. “The Virology and Immunobiology of Lymphocytic Choriomeningitis Virus Infection”. Advances in Immunology 30 (1980): 275-331.

Citation

Citation: Aditya Sharma., et al. “Lymphocytic Choriomeningitis". Acta Scientific Veterinary Sciences 4.12 (2022): 10-12.

Copyright

Copyright: © 2022 Aditya Sharma., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.