Acta Scientific Veterinary Sciences (ISSN: 2582-3183)

Research Article Volume 4 Issue 11

Immune Stimulatory Effects of Saccharomyces Cerevisiae in shrimp (Penaeus Vannamei) Diets

Govindharaj Sathish Kumar1,2*, Nathan Felix2, Elangovan Prabu2 and Kalidoss Manikandan2

1Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Institute of Fisheries Post Graduate Studies (IFPGS), Chennai, India

2Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Directorate of Incubation and Vocational Training in Aquaculture (DIVA), Chennai, India

*Corresponding Author: Govindharaj Sathish Kumar, Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Institute of Fisheries Post Graduate Studies (IFPGS), Chennai, India.

Received: September 06, 2022; Published: October 12, 2022


Pacific white shrimp (Penaeus vannamei) culture is the dominant shrimp aquaculture practice worldwide owing to the advantages of having high growth performance, good flesh taste, and high consumer preference. However, shrimp diseases caused by bacteria and viruses frequently lead to serious economic losses for shrimp aquaculture industries. As a consequence, the application of antibiotics and chemotherapeutants has been increased to prevent disease outbreaks, and as a result, the aquaculture industries have been polluted. Therefore, various alternative methods have been developed to prevent shrimp production from disease outbreaks. Yeast is a microbial ingredient and it has been widely used for a very long time as an application of probiotics to prevent diseases and improve the health status of shrimp through feed or water. In recent years, due to their good nutrient profile and bioactive contents, various yeast and yeast products have been used as either ingredient or additive in aqua diets to protect against diseases through increasing the immune responses of various commercial farmed shrimp and fishes. Therefore, this article is designed to discuss the importance of Saccharomyces cerevisiae in the Pacific white shrimp diet as well as the effects of growth performance, immune stimulants, and antioxidant status on the Pacific white shrimp.

Keywords: Alternative to Antibiotics; Feed Additive; Immune Stimulant; Pacific White Shrimp; Saccharomyces Cerevisiae


  1. Abu-Elala NM., et al. “Influence of dietary fermented Saccharomyces cerevisiae on growth performance, oxidative stress parameters, and immune response of cultured Oreochromis niloticus”Fish Physiology and Biochemistry2 (2020): 533-545.
  2. Acar U., et al. “Evaluation of the effects of essential oil extracted from sweet orange peel (Citrus sinensis) on growth rate of tilapia (Oreochromis mossambicus) and possible disease resistance against Streptococcus iniae”.Aquaculture 437 (2015): 282-286.
  3. Adeniyi OV., et al. “Growth performance and nutrient digestibility of Clarias gariepinus (Burchell 1822) fed diets fortified with Tamarindus indica pulp and leaf meal”. Asian Fisheries Science1 (2018): 17-31.
  4. Ayiku S., et al. “Effects of reducing dietary fishmeal with yeast supplementations on Litopenaeus vannamei growth, immune response and disease resistance against Vibrio harveyi”Microbiological Research 239 (2020): 126554.
  5. Ayiku S., et al. “Effects of dietary yeast culture on shrimp growth, immune response, intestinal health and disease resistance against Vibrio Harveyi”Fish and Shellfish Immunology 102 (2020): 286-295.
  6. Burgents JE., et al. “Disease resistance of Pacific white shrimp, Litopenaeus vannamei, following the dietary administration of a yeast culture food supplement”. Aquaculture1-4 (2004): 1-8.
  7. Chen XQ., et al. “Effects of dietary hydrolyzed yeast (Rhodotorula mucilaginosa) on growth performance, immune response, antioxidant capacity and histomorphology of juvenile Nile tilapia (Oreochromis niloticus)”. Fish and Shellfish Immunology90 (2019): 30-39.
  8. Chowdhury DK., et al. “Feeding turmeric in combination with ginger or garlic enhances the digestive enzyme activities, growth and immunity in Labeo rohita fingerlings”. Animal Feed Science and Technology277 (2021): 114964.
  9. Dash G., et al. “Evaluation of paraprobiotic applicability of Lactobacillus plantarum in improving the immune response and disease protection in giant freshwater prawn, Macrobrachium rosenbergii (de Man, 1879)”. Fish and Shellfish Immunology1 (2015): 167-174.
  10. Gul P and Bakht J. “Antimicrobial activity of turmeric extract and its potential use in food industry”. Journal of Food Science and Technology 4 (2015): 2272-2279.
  11. Guo J., et al. “Effects of nucleotides on growth performance, immune response, disease resistance and intestinal morphology in shrimp Litopenaeus vannamei fed with a low fish meal diet”. Aquaculture International4 (2016): 1007-1023.
  12. Guo Y., et al. “Effects of dietary yeast culture on health status in digestive tract of juvenile Pacific white shrimp Litopenaeus Vannamei”Fish and Shellfish Immunology Reports (2022): 100065.
  13. Ishida Y., et al. “New detection and separation method for amino acids by high-performance liquid chromatography”. Journal of Chromatography A 204 (1981): 143-148.
  14. Jin M., et al. “Dietary yeast hydrolysate and brewer's yeast supplementation could enhance growth performance, innate immunity capacity and ammonia nitrogen stress resistance ability of Pacific white shrimp (Litopenaeus vannamei)”. Fish and Shellfish Immunology 82 (2018): 121-129.
  15. Kumar P., et al. “Effects of dietary synbiotic on innate immunity, antioxidant activity and disease resistance of Cirrhinus mrigala juveniles”. Fish and Shellfish Immunology 80 (2018): 124-132.
  16. Labrador JRP., et al. “Effect of garlic powder-supplemented diets on the growth and survival of Pacific white leg shrimp (Litopenaeus vannamei)”. Cogent Food and Agriculture1 (2016): 1210066.
  17. Lawhavinit OA., et al. “Study on effects of ethanol tumeric (Curcuma longa Linn.) extract on Vibrio spp., growth and immunity of white shrimp (Litopenaeus vannamei)”. In Proceedings of the 48th Kasetsart University Annual Conference, Kasetsart, 3-5 March, 2010. Subject: Fisheries. Kasetsart University (2010).
  18. Livak KJ and Schmittgen TD. “Analysis of relative gene expression data using real-time quantitative PCR and the 2- ΔΔCT method”. Methods4 (2001): 402-408.
  19. Phiwsaiya K., et al. “A natural Vibrio parahaemolyticus Δ pirA Vp pirB Vp+ mutant kills shrimp but produces neither Pir Vp toxins nor acute hepatopancreatic necrosis disease lesions”. Applied and Environmental Microbiology16 (2017): e00680-00717.
  20. Pongpet J., et al. “Partial replacement of fishmeal by brewer's yeast (Saccharomyces cerevisiae) in the diets of Thai Panga (Pangasianodon hypophthalmus × Pangasius bocourti)”. Aquaculture Nutrition3 (2016): 575-585.
  21. R Miles and S Bootwalla. “Direct-fed microbials in animal production, Direct-fed microbials in animal production A review” (1991): 117-132.
  22. Tassanakajon A., et al. “Discovery of immune molecules and their crucial functions in shrimp immunity”. Fish and Shellfish Immunology4 (2013): 954-967.
  23. Vanichkul K., et al. “Immunological and bactericidal effects of turmeric (Curcuma longa Linn.) extract in pacific white shrimps (Litopenaeus vannamei Boone)”. Agriculture and Natural Resources5 (2010): 850-858.
  24. Yang C., et al. “Phytogenic compounds as alternatives to in-feed antibiotics: potentials and challenges in application”. Pathogens1 (2015): 137-156.
  25. Zahran E., et al. “Effects of dietary Astragalus polysaccharides (APS) on growth performance, immunological parameters, digestive enzymes, and intestinal morphology of Nile tilapia (Oreochromis niloticus)”. Fish and Shellfish Immunology1 (2014): 149-157.
  26. Zhang P., et al. “Effects of dietary yeast culture on growth performance, immune response and disease resistance of gibel carp (Carassius auratus gibelio CAS Ⅲ)”. Fish and Shellfish Immunology 82 (2018): 400-407.
  27. Zhang X., et al. “Effects of yeast culture substituting fishmeal on growth, nonspecific immunity, intestinal, and hepatopancreatic histology of Litopenaeus vannamei”Journal of the World Aquaculture Society (2022).


Citation: Niha Ayman., et al. “Transformative Role of Gaushalas in Conversion of Waste to Wealth: A Way Forward to Curb the Stray Cattle Menace".Acta Scientific Veterinary Sciences 4.11 (2022): 67-71.


Copyright: © 2022 Niha Ayman., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate35%
Acceptance to publication20-30 days
Impact Factor1.008

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is June 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US