Devendra Pathak¹*, Neelam Bansal¹, Opinder Singh¹, Kuldip Gupta² and SPS Ghuman³

¹Department of Veterinary Anatomy, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India
²Department of Veterinary Pathology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India
³Teaching Veterinary Clinical Complex, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India

*Corresponding Author: Devendra Pathak, Department of Veterinary Anatomy, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.

Received: April 11, 2022 Published:

Abstract

The steroid hormone, progesterone, is a key modulator of the normal reproductive functions of animals. The goal of this study was to see how progesterone receptors were distributed in distinct segments of the buffalo oviduct during the follicular and luteal phases of the estrous cycle. Oviducts from twelve buffaloes (six each during both the phases) were collected from the local abattoir. Blood samples were collected before the slaughter of the animal to estimate levels of estrogen and progesterone hormones. The cellular distribution of progesterone receptor (PR) was examined using the immunohistochemical technique. The PR was localized in cells of mucosal lining, connective tissue cells, oviductal glands, muscular layer, and serosal covering in different segments of the oviduct. In lamina epithelialis, both ciliated and secretory cell types were positive for PR. Infundibulum and ampulla had a higher number of PR positive cells which as compared to utero tubal junction was statistically significant (P < 0.05). The infundibulum, ampulla, and isthmus showed more population of PR-positive cells during the follicular phase of the estrous cycle when compared to the luteal phase (P < 0.05). The data on the percentage of PR-positive cells and hormone analysis showed that the PR expression was higher during the estradiol dominance.

Keywords: Buffalo; Estrous Cycle; Immunohistochemistry; Oviduct; Progesterone Receptor

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Citation

Citation: Devendra Pathak., et al. “Immunolocalization of Progesterone Receptor (PR) During Different Phases of Estrous Cycle in the Oviduct of Water Buffaloes". Acta Scientific Veterinary Sciences 4.5 (2022): 77-85.

Copyright

Copyright: © 2022 Devendra Pathak., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.