Scrub Typhus: A Threat to ‘Tsutsugamushi Triangle’
Parul*, Barkha Sharma, Udit Jain, Raghavendra P Mishra, Gourab Basak and Shikhar Karan Verma
Department of Veterinary Public Health, DUVASU, Mathura, India
*Corresponding Author: Parul, Department of Veterinary Public Health, DUVASU, Mathura, India.
Received:
March 16, 2022; Published: March 29, 2022
Abstract
Scrub typhus, caused by Orientia tsutsugamushi, is an important vector-borne disease that has been classified a neglected tropical zoonosis. The ecology of the disease is complex and less understood thus has more public health implication than other zoonotic diseases. About a million cases of scrub typhus are reported worldwide annually and the disease is associated with high mortality. It is endemic in geographically confined area of the Asia-Pacific termed as the Tsutsugamushi triangle’, which is bound by Siberia and Kamchatka peninsula to the north, Australia to the south, Japan to the east and Afghanistan and India to its west, covering Northern Australia, South and Southeast Asia, the Indian subcontinent and Pacific Ocean. There has been a resurgence of scrub typhus across India in the recent years and the disease has re-emerged as a major cause of acute undifferentiated febrile illnesses (AUFI) in humans with high morbidity and mortality. Thus better understanding of scrub typhus epidemiology is needed to put in place appropriate public health interventions to reduce the burden of the disease globally. This comprehensive review provides summary of work, investigation of this pathogen in vectors and updates for understanding the complexity of scrub typhus.
Keywords:Scrub Typhus; Orientia Tsutsugamushi; Tsutsugamushi Triangle; Vector-Borne Zoonosis
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