Anil Kumar Sharma¹*, Roshan Lal¹, Jyotsna Sharma² and Ankush³

¹Department of Animal Husbandry, Himachal Pradesh, India
²Ayush Department, Himachal Pradesh, India
³Tata consultancy services, India

*Corresponding Author:Anil Kumar Sharma, Department of Animal Husbandry, Himachal Pradesh, India.

Received: March 01, 2022; Published: March 14, 2022

Abstract

Dealing with veterinary oncology cases is often a great challenge for veterinarians in Himachal Pradesh. Only chemotherapy available for benign tumors is Vincristine which is ineffective against perianal and rectal tumors. Not only the wide range of presenting signs and cancer types require a veterinarian to be constantly vigilant, but also the high prevalence rates of some cancers mean that the battle against cancer in pets is seemingly constant. Acellularization of xenogenic biomaterials has been highly desired for implantation without considerable adverse inflammatory and immune responses. In a prospective non-randomized study, we evaluated the effectiveness of grafting the pig’s diaphragm (freshly sacrificed) into the dead space created post-surgery in the rectal, anal and perianal regions in a Labrador dog (aged approx 4 years) suffering from perianal adenoma and epithelioma in Veterinary Polyclinic, Rampur Bushahar. The graft got rejected after 8 days of surgery. We performed another grafting surgery with fresh pig diaphragm which again lasted for next 8 days, the healing of the tissue below the grafted pig diaphragm was seen upto 80%. After 2 months of surgery tissue healing upto 90% was observed. This indicates that even if the graft gets selected or rejected the healing of the tissue happens and the post-sugery dead space got healed using this technique. Both way graft has its importance. Hence this technique of xenografting pig’s diaphragm into the skin tissue of dog is better alternative for expensive chemotherapy which is commonly used in peri-anal adenoma treatment.

Keywords: Dog; Peri-Anal Tumor; Pig Diaphragm; Grafting; Tissue Healing

References

1. Berrocal A., et al. “Canine perianal tumors”. Journal of Veterinary Medicine 36 (1989): 739-749.
2. Goldschmidt MH., et al. “Histological classification of epithelial and melanocytic tumors of the skin, World Health Organisation International histological classification of tumours of domestic animals, Second Series, Vol III. Washington DC, 27-8. 300”. Acta Veterinaria (Beograd)2-3 (1998): 285-302.
3. Grier RL., et al. “Hypertermic treatment of superficial tumors in cats and dogs”. Journal of the American Veterinary Medical Association 177 (1980): 227-233.
4. Holt P. “Anal and perianal surgery in dogs and cats”. In Practice 7 (1985): 82-89.
5. La Rue SM., et al. “Radiation therapy of thoracic and abdominal tumors”. Seminars in Veterinary Medicine and Surgery (Small Animal) 10 (1995): 190-196.
6. Liska WD. “Anorectal and perianal cryosurgery”. Veterinary Clinics of North America: Small Animal Practice 10 (1980): 803-820.
7. Pisani G., et al. “Androgen receptor expression in normal, hyperplastic and neoplastic hepatoid glands in the dog”. Research in Veterinary Science 81 (2006): 231-326.
8. Rols MP., et al. “Electrochemotherapy of horses. A preliminary clinical report”. Biolectrochemistry 55 (2002): 101-105.
9. Shelley BA. “Use of the carbon dioxide laser for perianal anal and rectal surgery”. Veterinary Clinics of North America Small Anim Pract 32 (2002): 621-637.
10. Tozon N., et al. “Effective treatment of perianal tumors in dogs with electrochemotherapy”. Anticancer Research 2A (2005): 839-845.
11. Vail DM., et al. “Perianal adenocarcinoma in the canine male: A retrospective study of 41 cases”. Journal of the American Animal Hospital Association 26 (1990): 329-334.
12. Kumar V., et al. “Use of bubaline acellular diaphragm matrix for umbilical hernioplasty in pigs”. Archives on Veterinary 1 (2015): 49-58.
13. Weiss E and Frese E. “Tumours of the skin. In: Bulletin of the World Health Organisation, International histological classification of tumours of domestic animals”. Geneva, World Health Organization 50 (1974): 82.
14. WHO handbook for reporting results of cancer treatment. Geneva, WHO Offset Publications 48 (1997): 22-27.
15. Wilson GP and Hayes HM. “Castration for treatment of perianal gland neoplasms in the dog”. Journal of the American Veterinary Medical Association 174 (1979): 1301-1303.
16. Withrow SJ. “Perianal Tumors. In: Withrow SJ, MacEwen EG, editors, Small Animal Clinical Oncology, 2^nd, Philadelphia: WB Saunders Co (1996): 261-267.

Citation

Citation: Anil Kumar Sharma., et al. “Surgical Grafting of Pig’s Diaphragm in a Dog with Rectal and Perianal Adenoma and Epithelioma After Removing the tumor Mass; an Alternative for Expensive Chemotherapy Treatment”.Acta Scientific Veterinary Sciences 4.4 (2022): 59-63.

Copyright

Copyright: © 2022 Anil Kumar Sharma., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.