Acta Scientific Veterinary Sciences (ISSN: 2582-3183)

Review Article Volume 4 Issue 3

Canine Distemper, Clinical Update, Based on our Medical Experience and Scientific Evidence

Jorge Luis Sánchez Palomino*, Lidia Leonor Paredes Lozano, Javier Alberto Schuldt Cruz, Gustavo Adolfo Vásconez Galarza and Roberto Carlos Medina Burbano

Faculty of Agricultural Sciences, School of Veterinary Medicine and Zootechnics, Technical University of Babahoyo, Ecuador

*Corresponding Author: Jorge Luis Sánchez Palomino, Faculty of Agricultural Sciences, School of Veterinary Medicine and Zootechnics, Technical University of Babahoyo, Ecuador.

Received: January 27, 2022; Published: February 17, 2022


The objective of this research is to provide the clinical update of the canine Distemper, based on our experience with medical practice and scientific evidence, to provide updated support to multidisciplinary medical teams, to describe, address, and identify the most useful methods For diagnosis, apply urgent therapies to try to reduce the high morbidity and mortality caused by this health phenomenon, and be able to predict, considering that it is the most aggressive among many of the pathologies that canines present today and other non-domestic species. It was investigated, between the months of September to December 2021, analyzing the data collected to have a current vision of the behavior of this lethal noxa.

Keywords: Canine Distemper; Diagnosis; Treatments; Prognoses


  1. Apple JG and Summers BA. Canine distemper: Current Status. IVIS Org (2015).
  2. Astete JM. “Pathogenesis of Canine Distemper Virus”. Srivis (2015).
  3. Beineke A., et al. “Cross-species transmission of canine distemper virus-an update”. One Health 1 (2015): 49-59.
  4. Bogdanchikova N., et al. “Silver nanoparticles composition for treatment of distemper in dogs”. International Journal of Nanotechnology1-3 (2016): 225-235.
  5. Lawns PF., et al. “Modulation of the immune response during canine distemper virus infection. Therapeutic implications and in the development of vaccines”. Archives of Medical Science 2 (2015).
  6. Duque-Valencia J., et al. “Phylogenomic Analysis of Two Co-Circulating Canine Distemper Virus Lineages in Colombia”. Pathogens 1 (2020): 26.
  7. Ferreyra Poicón E. “Use of Azathioprine in the treatment of Distemper”. REDVET 1 (2015).
  8. Greene C. “Infectious diseases of the dog and cat”. 3rd Buenos Aires: Inter-Medica (2008): 28-45.
  9. Hao X., et al. “Multiplex PCR methods for detection of several viruses associated with canine respiratory and enteric diseases”. PLoS One3 (2019): e0213295.
  10. ICTV International Committee on Taxonomy of Viruses. Virus taxonomy: 2020 release (2020).
  11. Lempp C. “New aspects of the pathogenesis of canine leukoencephalitis disease”. NCBI7 (2015).
  12. Martella V., et al. “Canine distemper virus”. Veterinary Clinics of North America: Small Animal Practice 38 (2018): 787-797.
  13. Panzera L and R Von Messling. “Canine Distemper: Current Status”. Veterinary Clinics of North America: Small Animal Practice 51 (2019): 232-299.
  14. Pinotti MA. “Canine Distemper: Evaluation of two therapeutic alternatives and characterization of clinical-epidemiological aspects in the City of Santa Fe, during the years 1998-2009. Thesis. Hope: National University of the Coast”. Faculty of Veterinary Sciences (2015).
  15. Rauller X and Centellas C. “Neurological canine distemper”. Veterinary Division. Newsletter2 (2015).
  16. Rendon-Marin S., et al. “Tropism and molecular pathogenesis of canine distemper virus”. Virology Journal 1 (2019): 30.
  17. Rubio A., et al. “Guidelines for the vaccination of dogs (canines) and cats (felines) in Peru”. Research Review see Peru4 (2018): 1463-1474.
  18. Rudd PA., et al. “Canine Distemper Virus Uses both the Anterograde and the Hematogenous Pathway for Neuroinvasion”. Journal of Virology22 (2015).
  19. Santos La Torre J. “Presence of Antibodies against Canine Distemper Virus in common dogs (Canis Lupus familiaris) from rural areas inhabited by the sechura fox (Lycalopex sechurae). Thesis. Lima Peru. National University of San Marcos”. Faculty of Veterinary Medicine (2015).
  20. Uhl EW., et al. “New world origin of canine distemper: Interdisciplinary insights”. International Journal of Paleopathology (2019): 266-278.
  21. Valerio Carvalho O., et al. “Immunopathogenic and Neurologica lMechanisms of Canine Distemper Virus”. Advances in Virology (2015).
  22. Virbac Laboratories. “Update on Canine Distemper Therapeutics”. Use of Feline Recombinant Interferon (2015).
  23. “General aspects of the distemper complex in the canine”.
  24. “Moquillo”.
  25. “The Merck Veterinary Manual”.
  26. Zhao J., et al. “Viral Pathogenesis, Recombinant Vaccines, and Oncolytic Virotherapy: Applications of the Canine 47 Distemper Virus Reverse Genetics System”. Viruses 3 (2020): 339.


Citation: Jorge Luis Sánchez Palomino., et al. “Canine Distemper, Clinical Update, Based on our Medical Experience and Scientific Evidence”. Acta Scientific Veterinary Sciences 4.3 (2022): 45-51.


Copyright: © 2022 Jorge Luis Sánchez Palomino., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate35%
Acceptance to publication20-30 days
Impact Factor1.008

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