Acta Scientific Veterinary Sciences (ISSN: 2582-3183)

Research Article Volume 4 Issue 2

Clinical Efficacy of Tiletamine-Zolazepam and Ketamine-Diazepam Combination on Quality of Anesthesia for Ovariohysterectomy in Dog

Prashant Dilip Salve1*, Milind Gonduji Thorat2, Ratnakar Vasantrao Raulkar3, Ravindrakumar Imdeo Hatzade4, Mahesh V Ingawale5, Mahesh Babasaheb Pawar1 and Avinash Ganpat Jadhav1

1M V Sc Student, Department of Veterinary Surgery and Radiology, Maharashtra, India
2Professor and Head, Department of Veterinary Surgery and Radiology, Maharashtra, India
3Assistant Professor, Department of Veterinary Surgery and Radiology, Maharashtra, India
4Department of Veterinary Medicine, Maharashtra, India
5Assistant Professor, Department of Veterinary Gynaecology and Obstetrics, Maharashtra, India

*Corresponding Author: Prashant Dilip Salve, M V Sc Student, Department of Veterinary Surgery and Radiology, Maharashtra, India.

Received: January 3, 2022; Published: January 31, 2022


The present study was undertaken to compare the anesthetic efficacy of tiletamine-zolazepam and ketamine-diazepam combination in 12 bitches presented to the TVCC, PGIVAS, Akola for ovariohysterectomies. These 12 dogs were randomly divided into two equal groups. Group I dogs were anaesthetized with tiletamine-zolazepam and Group II dogs were anaesthetized with ketamine-diazepam combination. In both the groups xylazine was used as a pre-anaesthetic. Quality of anaesthesia, assessment of anaesthesia and clinico-physiological parameters were recorded at different time intervals during the study period. The quality of anaesthesia was found to be superior in group I as compared to group II. Induction of anaesthesia was rapid and smooth in both the groups. However, duration of anaesthesia and recovery time was longer in group I as compared to group II. Smooth recovery was observed in both the groups. Rectal temperature and respiration rate was showing decreasing trend in both the groups however, these values were within normal physiological range. Heart rate in both the group was showing decreasing trend with the appearance of bradycardia during recovery in both the groups. SpO2 level was fluctuating within normal physiological limit in both the groups. Quality of muscle relaxation of tiletamine was better than ketamine and overall quality of anaesthesia of tiletamine-zolazepam was found to be superior as compare to ketamine-diazepam combination.

Keywords: Dog; Ovariohysterectomy; Tiletamine-Zolazepam; Ketamine-Diazepam; Xylazine


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Citation: Prashant Dilip Salve., et al. “Clinical Efficacy of Tiletamine-Zolazepam and Ketamine-Diazepam Combination on Quality of Anesthesia for Ovariohysterectomy in Dog". Acta Scientific Veterinary Sciences 4.2 (2022): 51-56.


Copyright: © 2022 Prashant Dilip Salve., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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