Acta Scientific Veterinary Sciences (ISSN: 2582-3183)

Research Article Volume 3 Issue 12

Effect of Sodium Butyrate, Sodium Salt of Medium Chain Fatty Acids (Dicosan) in Combatting Clostridium perfringens Induced Necrotic Enteritis in Broiler Chicken

Dayaram Suryawanshi*, Sonali Shete, Rutuja Shelke, Mrugali Patil, Hrishikesh Kamat and Pavan Pawar

Department of Pathology, Omega Laboratories, India

*Corresponding Author: Dayaram Suryawanshi, Department of Pathology, Omega Laboratories, India.

Received: November 10, 2021; Published: November 29, 2021


Present study was conducted to evaluate the efficacy of sodium butyrate, sodium salts of medium chain fatty acids and their combinations against the induced necrotic enteritis in broiler chickens. The study was undertaken on 480 broiler birds. Birds were distributed in 5 groups viz. Normal control (NC), Negative control (NC+C), sodium salt of butyrate (SB+C), Medium chain Fatty acids (Dicosan) (MCFA+C) and SB + MCFA (Dicosan+)+C groups. Standard management practices and vaccinations were carried out. On day 18 birds were inoculated orally with suspension of Clostridium perfringens, and on day 4, 5 and 6 post infections, one bird was sacrificed from each replicate. The gross pathological score out of 4 was 3.4806, 1.882, 1.68 and 0.73 respectively in NC, NC+C, SB+C , MCFA+C and SB+MCFA+C, respectively. Microscopic score was 3.2652, 1.378, 1.296 and 0.7318, respectively for groups NC, NC+C, SB+C, MCFA+C and SB+MCFA+C. Fecal culture was carried out before induction of infection, during course of infection and at the end of experiment i.e. on day 42. Group SB + MCFA+ challenge showed better reduction in clostridium count as compared to other treatment groups. Negative control + challenge group showed higher clostridium count as compared to all treatment groups.

Keywords: Sodium Salts of Butyrate; Medium Chain Fatty Acids; Clostridium perfringens; Necrotic Enteritis


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Citation: Dayaram Suryawanshi., et al. “Effect of Sodium Butyrate, Sodium Salt of Medium Chain Fatty Acids (Dicosan) in Combatting Clostridium perfringens Induced Necrotic Enteritis in Broiler Chicken". Acta Scientific Veterinary Sciences 3.12 (2021): 101-105.


Copyright: © 2021 Dayaram Suryawanshi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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