Acta Scientific Veterinary Sciences (ISSN: 2582-3183)

Research Article Volume 3 Issue 9

Evaluation of Oxidative Stress Index and Some Biochemical Parameters in Neonatal Calves with Diarrhea

Enes Akyüz1 and Abdulsamed Kükürt2*

1Department of Internal Medicine, Kafkas University, Turkey
2Department of Biochemistry, Kafkas University, Turkey

*Corresponding Author: Abdulsamed Kükürt, Faculty of Veterinary Medicine, Department of Biochemistry, Kafkas University, Turkey.

Received: July 20, 2021; Published: August 31, 2021

Abstract

  The aim of this study was to evaluate the total oxidant/antioxidant (TOC/TAC), oxidative stress index (OSI), and alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine (CREA), and UREA levels in neonatal calves with diarrhea. In the study, 15 calves (0-10 days old Simmental, Swiss brown, or hybrid) brought to the clinic with the complaint of diarrhea formed the disease group. 15 healthy calves under the same care/feeding conditions formed the control group. TAC and TOC concentrations were measured by commercial kits. OSI results were calculated with the formula in which TOC and TAC results were proportioned. Serum ALT, AST, CREA, and UREA concentrations were measured with an autoanalyzer. The findings showed that TAC and TOC concentrations were affected by clinical diarrhea. Thus, it increased the oxidative stress index (OSI) (p < 0.001). Also, the ALT, AST, CREA, and UREA levels of diarrheal calves were found to be significantly higher than the levels of healthy calves. Consequently, it was observed that the oxidative damage in diarrhea caused an increase in OSI levels.

Keywords: Neonatal Calves; Diarrhea; Oxidative Stress; Oxidant; Antioxidant; OSI

References

  1. Meganck V., et al. “Evaluation of a protocol to reduce the incidence of neonatal calf diarrhoea on dairy herds". Preventive Veterinary Medicine1 (2015): 64-70.
  2. Erdoǧan HM., et al. “Dairy farming in Kars district, Turkey: III. Neonatal calf health". Turkish Journal Of Veterinary And Animal Sciences3 (2009): 185-192.
  3. Erkiliç EE., et al. “Salivary and serum levels of serum amyloid A, haptoglobin, ceruloplasmin and albumin in neonatal calves with diarrhoea". Kafkas Universitesi Veteriner Fakultesi Dergisi4 (2019): 583-586.
  4. Akyüz E., et al. “The effects of flui̇d resuscitation on the hemodynamic parameters of experimental induced endotoxemia in the neonatal calves". Eurasian Journal of Veterinary Sciences4 (2016): 246-254.
  5. Cho Y., et al. “An overview of calf diarrhea - infectious etiology, diagnosis, and intervention". Journal of Veterinary Science1 (2014): 1-17.
  6. Akyüz E. “Kars Bölgesindeki Neonatal Buzağılarda Sıklıkla Karşılaşılan İshal Kaynaklı Sepsis Nedenleri". Tüm Yönleri İle Kuzey Doğu Anadolu Bölgesinde Hayvancılık (2020): 401-423.
  7. Aydogdu U., et al. “Effect of combinations of intravenous small-volume hypertonic sodium chloride, acetate Ringer, sodium bicarbonate, and lactate Ringer solutions along with oral fluid on the treatment of calf diarrhea". Polish Journal of Veterinary Sciences2 (2018): 273-280.
  8. Akyüz E., et al. “Neonatal Buzağı İshalleri ve Sepsis". Kafkas University Institute of Natural and Applied Science Journal 10 (2017): 181-191.
  9. Kükürt A., et al. “Nitrik oksit, nitrik oksit sentaz ve dişi üreme sistemindeki rolleri". In: Evereklioğlu C, editor. Sağlık Bilimleri Alanında Akademik Çalışmalar II (2020) 113-123.
  10. Kükürt A., et al. “Thiols: Role in Oxidative Stress-Related Disorders". Lipid Peroxidation (2021).
  11. Kükürt A., et al. “Kisspeptin: Role in Female Infertility". In: Marsh C, editor. Reproductive Hormones (2021).
  12. Kükürt A.,“Doğal bir antioksidan olarak propolis tedavisinin koruyucu etkileri". In: Evereklioğlu C, editor. Sağlık Bilimlerinde Teori ve Araştırmalar II (2020): 501-515.
  13. Kuru M., et al. “Clinical Use of Progesterone and Its Relation to Oxidative Stress in Ruminants". In: Drevenšek G, editor. Sex Hormones in Neurodegenerative Processes and Diseases. (2018): 303-327.
  14. Erel O. “A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation". Clinical Biochemistry 37 (2004): 277-285.
  15. Erel O. "A new automated colorimetric method for measuring total oxidant status". Clinical Biochemistry 38 (2005): 1103-1111.
  16. Kaya I., et al. “Investigation of Serum Oxidative Stress Index and Paraoxonase Activity Levels in Colostrum Period of Dairy Cows". International Journal of Livestock Research 6 (2016): 1-7.
  17. Miller JK., et al. “Oxidative Stress, Antioxidants, and Animal Function". Journal of Dairy Science9 (1993): 2812-2823.
  18. Kirmizigül AH., et al. "Oxidative stress and total sialic acid levels in sheep naturally infected with pox virus" Pakistan Veterinary Journal 3 (2016): 312-315.
  19. Deveci HA., et al. "Serum paraoxonase activity and total sialic acid in sheep with foot and mouth disease". Medycyna weterynaryjna3 (2018): 199-202.
  20. Merhan O., et al. "Investigation of Oxidative Stress Index and Lipid Profile in Cattle with Brucellosis". Kafkas Universitesi Veteriner Fakultesi Dergisi6 (2017): 933-937.
  21. Kaya S., et al. "The Impact of Endometritis on Specific Oxidative Stress Parameters in Cows". Journal of the Hellenic Veterinary Medical Society2 (2017): 231-236.
  22. Deveci HA., et al. "Evaluation of paraoxonase activity, total sialic acid and oxidative stress in sheep with ecthyma contagiosa". Kafkas Üniversitesi Veteriner Fakültesi Dergisi 3 (2017): 453-457.
  23. Erkiliç EE., et al. "Determination of some Oxidative Stress and Inflammation Markers in Serum, Blood and CSF in Cattle with Head-Eye Form of Malignant Catarrhal Fever". Kafkas Üniversitesi Veteriner Fakültesi Dergisi4 (2017): 515-519.
  24. Deveci H.A., et al. "Biochemical and Histopathological Changes of Babesiosis in Naturally Infected Sheep in Gaziantep Region". Fresenius Environmental Bulletin 26 (2017): 4883-4889.
  25. Deveci HA., et al. "Determination of Serum Paraoxonase Activity, Total Sialic Acid Concentration, and Oxidative Status in Cattle with Clinical Mastitis". International Journal of Veterinary Science3 (2017): 136-140.
  26. Lykkesfeldt J., et al. “Oxidants and antioxidants in disease: Oxidative stress in farm animals". The Veterinary Journal3 (2007): 502-511.
  27. Vaya J., et al. “Nutritional Antioxidants Mechanisms of Action, Analyses of Activities and Medical Applications". Current Medicinal Chemistry - Immunology, Endocrine and Metabolic Agents 1 (2001): 99-117.
  28. Halliwell B., et al. “Free Radicals in Biology and Medicine". Free Radical Biology and Medicine (2015).
  29. Akyüz E., et al. “The Determination of Oxidative Stress Index of Enteritis Caused by Escherichia coli K99 Strain in Simmental New-born Calves". International Turkish Veterinary Internal Medicine Congress (2017): 176-177.
  30. Gelen V., et al. "The protective effects of hesperidin and curcumin on 5-fluorouracil-induced nephrotoxicity in mice". Environmental Science and Pollution Research (2021): 1-10.
  31. Kaya I., et al. "Effect of ellagic acid on some oxidative stress parameters and cyclooxygenase-2 reactivity in mice with experimental gastric injury". Japanese Journal of Gastroenterology and Hepatology3 (2019): 1-9.
  32. Kaya I., et al. "Investigation of oxidative stress index in pyridine and ellagic acid treated mice". Eurasian Journal of Veterinary Sciences3 (2015): 148-151.
  33. Deveci HA., et al. "Akut klorprifos-etil toksikasyonunda kafeik asit fenetil esterin total sialik asit, nitrik oksit ve aminotransferaz düzeylerine etkisi". Kafkas Üniversitesi Fen Bilimleri Enstitüsü Dergisi1 (2016): 39-45.
  34. Ogun M., et al. "Oleuropein ameliorates arsenic induced oxidative stress in mice". Journal of Trace Elements in Medicine and Biology 36 (2016): 1-6.
  35. Deveci HA., et al. "Protective role of caffeic acid phenethyl ester against to chlorpyrifos-ethyl acute poisoning". Ankara Üniversitesi Veteriner Fakültesi Dergisi4 (2015): 255-260.
  36. Karapehlivan M., et al. "The beneficial effects of silymarin administration against nicotine induced oxidative stress in mice". Journal of Cellular Neuroscience and Oxidative Stress1 (2016): 561.
  37. Deveci HA., et al. "Protective Effect of Caffeic Acid Phenethyl Ester on Cadmium-Induced Liver Toxicity: A Histopathological and Biochemistry Study". PREPRINT (Version 1) Environmental Science and Pollution Research (2021): 1-15.
  38. Kükürt A. "In vivo antioxidative activities of ellagic acid in indomethacin-induced gastric injury related oxidative stress". Journal of Cellular Neuroscience and Oxidative Stress (2021).
  39. Meral Ö., et al. “Septisemili buzağılarda lipid peroksidasyon düzeyi ve antioksidan enzim aktiviteleri". Ankara Üniversitesi Veteriner Fakültesi Dergisi 64 (2017): 161-164.
  40. Erkilic EE., et al. “Relationship between hepcidin and oxidant/antioxidant status in calves with suspected neonatal septicemia". Veterinary World 9 (2016): 1238-1241.
  41. Kabu M., et al. “Determination of pre and post treatment oxidative status and oxidative DNA damage in diarrheic calves". Indian Journal of Animal Research6 (2015): 830-833.
  42. Rodriguez C., et al. “Regulation of antioxidant enzymes: A significant role for melatonin". Journal of Pineal Research1 (2004): 1-9.
  43. Akyüz E., et al. “Neopterin, procalcitonin, clinical biochemistry, and hematology in calves with neonatal sepsis". Tropical Animal Health and Production 53 (2021).
  44. Dratwa-Chałupnik A., et al. “Calves with diarrhea and a water-electrolyte balance". Medycyna Weterynaryjna1 (2012): 65-72.
  45. Albayrak H., et al. “Determining Serum Haptoglobin and Cytokine Concentrations in Diarrheic Calves". Fırat Üniversitesi Sağlık Bilimleri Dergisi2 (2016): 113-117.

Citation

Citation: Enes Akyüz and Abdulsamed Kükürt. “Evaluation of Oxidative Stress Index and Some Biochemical Parameters in Neonatal Calves with Diarrhea". Acta Scientific Veterinary Sciences 3.9 (2021): 58-63.

Copyright

Copyright: © 2021 Enes Akyüz and Abdulsamed Kükürt. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
Impact Factor1.008

Indexed In





News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 10, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US