Evaluation of Oxidative Stress Index and Some Biochemical Parameters in
Neonatal Calves with Diarrhea
Enes Akyüz1 and Abdulsamed Kükürt2*
1Department of Internal Medicine, Kafkas University, Turkey
2Department of Biochemistry, Kafkas University, Turkey
*Corresponding Author: Abdulsamed Kükürt, Faculty of Veterinary Medicine, Department of Biochemistry, Kafkas University, Turkey.
Received:
July 20, 2021; Published: August 31, 2021
Abstract
The aim of this study was to evaluate the total oxidant/antioxidant (TOC/TAC), oxidative stress index (OSI), and alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine (CREA), and UREA levels in neonatal calves with diarrhea. In the study, 15 calves (0-10 days old Simmental, Swiss brown, or hybrid) brought to the clinic with the complaint of diarrhea formed the disease group. 15 healthy calves under the same care/feeding conditions formed the control group. TAC and TOC concentrations were measured by commercial kits. OSI results were calculated with the formula in which TOC and TAC results were proportioned. Serum ALT, AST, CREA, and UREA concentrations were measured with an autoanalyzer. The findings showed that TAC and TOC concentrations were affected by clinical diarrhea. Thus, it increased the oxidative stress index (OSI) (p < 0.001). Also, the ALT, AST, CREA, and UREA levels of diarrheal calves were found to be significantly higher than the levels of healthy calves. Consequently, it was observed that the oxidative damage in diarrhea caused an increase in OSI levels.
Keywords: Neonatal Calves; Diarrhea; Oxidative Stress; Oxidant; Antioxidant; OSI
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