Santos Ibarra Alejandro¹*, Flores Parra Violeta Elizabeth¹, Romano Hernandez Francisco Jose¹, Michel Vergara JA², López Rodríguez Samuel Eduardo¹, Macnally Jimmy¹, Gonzalez Berchelmann Lorenzo¹, Escarcega Preciado Jaime Arturo³ and Leal Almeida Manuel Gerardo³

¹Fertilità Medicina Reproductiva, Monterrey, Nuevo León, México
²CERFERTIL, Guadalajara, Jalisco, México
³Gestare, Chihuahua, Chihuahua, México

*Corresponding Author:

Received: June 02, 2026; Published: July 09, 2026

Objective: To characterize the distribution of serum Anti-Müllerian Hormone (AMH) concentrations according to age in a large
cohort of Mexican women and to generate clinically useful reference values for ovarian reserve assessment.
Materials and Methods: A retrospective observational study was conducted using hormonal records obtained from a clinical
database. Serum AMH determinations with documented age were included for women between 20 and 50 years of age. AMH
concentrations were analyzed according to age, and descriptive statistics together with age-specific percentiles were calculated for
each age group.
Results: A total of 8,989 AMH determinations corresponding to 8,539 women with documented age were included in the analysis.
Serum AMH concentrations showed a progressive decline with increasing age. In younger women, the median AMH concentration
was approximately 3.0 ng/mL, whereas in older women the median decreased to approximately 0.6 ng/mL. Percentile analysis
demonstrated substantial variability in AMH concentrations within each age group, with higher upper percentiles observed among
younger women. These findings allowed the construction of age-specific percentile curves describing ovarian reserve patterns in the
studied population.
Conclusions: Serum AMH concentrations demonstrate a clear age-dependent decline in this large cohort of Mexican women.
The reference values generated in this study may serve as a useful clinical tool for ovarian reserve assessment and individualized
reproductive counseling.
Keywords: Anti-Müllerian Hormone; AMH; Ovarian Reserve; Age-Specific Reference Values; Fertility; Mexican Women

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Citation

Citation: Santos Ibarra Alejandro., et al. “Distribution of Anti-Müllerian Hormone Levels According to Age in a Large Cohort of Mexican Women". Acta Scientific Reproductive Biology 1.1 (2026): 01-08.

Copyright

Copyright: © 2026 Santos Ibarra Alejandro., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.