Let’s Talk About Steroids
Nida Tabassum Khan*
Department of Biotechnology, Faculty of Life Sciences and Informatics, Balochistan University of Information Technology, Engineering and Management Sciences, Quetta, Balochistan, Pakistan
*Corresponding Author: Nida Tabassum Khan, Department of Biotechnology, Faculty of Life Sciences and Informatics, Balochistan University of Information Technology, Engineering and Management Sciences, Quetta, Balochistan, Pakistan.
Received:
March 01, 2023 Published: June 01, 2023
Abstract
Steroids are a group of terpenoid lipids broadly disseminated in nature that present a moderately unbending chemical conformation named gonane framed by four fused alicyclic rings. The oxidation state of the steroid core and the presence of various substitutional groups determines the specific properties/function of each steroidal molecule. Steroidal compounds assume significant role in organisms, including cell proliferation, stabilization of plasma membrane, regulation of cellular pathways etc. Steroids/steroidal intermediates are synthesised on large scale either synthetically or by means of microorganisms aided bioconversion reactions that are cost-effective and environmentally friendly.
Keywords: Cell signalling; Cortisone; Biotransformation; Sapogenins; Functionalization
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