Acta Scientific Pharmacology

Research Article Volume 3 Issue 11

Side Effects of The Antiemetic Drug Motilium (Domperidone) Studied on Ants as Models

Marie-Claire Cammaerts*

Independent Researcher, Retired from the Biology of Organisms Department, University of Brussels, Belgium

*Corresponding Author: Marie-Claire Cammaerts, Independent Researcher, Retired from the Biology of Organisms Department, University of Brussels, Belgium.

Received: October 10, 2022 Published: October 27, 2022

Abstract

The antiemetic active substance of Motilium, Domperidone, is very efficient, but is no longer authorized in France for children due to its side effects. These effects (reported e.g., in the notice for use joined to the drug package) concerns several health problems, but not many other physiological and ethological important traits which may be affected by Motilium consumption. We thus examined, on ants as models, if such impacts may occur. Motilium appeared to affect the ants’ food intake, activity, locomotion, orientation ability, audacity, sensory perception, social relationships, state of stress, cognition, learning and memory. The ants did not adapt themselves to the drug side effects, and developed dependence on its consumption. Motilium partly lost its effect in two hours, then became inefficient in about 12 more hours. Thus, Domperidone have effectively a lot of severe side effects. Researchers have found clinical analyses which allow predicting if the patients will suffer from this drug side effects. Therefore, since Motilium is very efficient, we propose to go on using it, but before using it to check if the patients could no suffer from side effects, and during the treatment (with the smallest possible dose and during the shortest possible time period) to monitor the patients as for the occurrence of side effects, e.g., decrease of activity and audacity, locomotor problems, social interrelations problems, stress, and dependence.

Keywords: Addiction, Audacity; Cognition; Nausea; Sensory Perception; Social Relationships

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Citation

Citation: Marie-Claire Cammaerts. “Side Effects of The Antiemetic Drug Motilium (Domperidone) Studied on Ants as Models". Acta Scientific Pharmacology 3.11 (2022): 09-23.

Copyright

Copyright: © 2022 Marie-Claire Cammaerts. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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