Devinder Kumar Maheshwari*, Sneha Bharti and Saara

University College of Pharmacy, Guru Kashi University, Talwandi Sabo, Bathinda, Punjab, India

*Corresponding Author: Devinder Kumar Maheshwari, University College of Pharmacy, Guru Kashi University, Talwandi Sabo, Bathinda, Punjab, India.

Received: September 28, 2022 Published: October 21, 2022

Abstract

In late year, the interest of plant-based medication, wellbeing items, drug, food supplements, neutraceuticals, cosmetic items, and so forth are expanding in both creating and created nations. Since plants contain antioxidant of natural origin like polyphenols, flavonoids, carotenoids, vitamin A, E and C. These antioxidants help to adjust chronic illnesses like diabetes, cardiovascular sicknesses, maturing, malignant growth and neurological infections. The free radicals are liable for the event of these infections. An enormous number of traditional plants are accessible with solid antioxidant profile, which can overcome such sicknesses that caused because of free extremists. Parthenium hysterophorus is one such conventional plants, which have cell reinforcement property and oversee different infections. It is a rich source of number of phytopharmaceuticals particularly phenolic mixes and flavonoids. Different samples of Parthenium hysterophorus aerial parts were arranged progressively arranged by expanding polarity using standard extraction strategies. Fundamental phytochemical screening indicated presence of bioactive classes of natural compounds such as triterpenoids, phenolic mixes and flavonoids in chloroform and methanol extracts of plant. The methanol extract of plant aerial parts exhibited maximum antioxidant activity with IC₅₀ value of 76.07 µg/ml, where as standard rutin showed IC₅₀ value 4.93 µg/m. The chloroform extract showed mild antioxidant activity with IC₅₀ value of 318.72 µg/ml. The bioactive methanol extract have shown presence of phenolic and flavonoid compounds, which have been reported to possess strong antioxidant activity.

Keywords: Antioxidant; Flavonoids; Herbal; Parthenium hysterophorus; Phenols

References

1. Panche AN., et al. “Flavonoids: an overview”. Journal of Nutritional Science 5 (2016): 1-15.
2. Dev S. “Ethnotherapeutic and modern drug development: The potential of Ayurveda”. Current Science 11 (1997): 909-928.
3. Kamboj VP. “Herbal medicine”. Current Science 1 (2000): 35-39.
4. Dhar ML., et al. “Screening of Indian plants for biological activity: Part I”. Indian Journal of Experimental Biology 7 (1968): 232-247.
5. Chatterjee I., et al. “Daboia russellii and Naja kaouthia venom neutralization by lupeol acetate isolated from the root extract of Indian sarsaparilla Hemidesmus indicus Br”. Journal of Ethnopharmacology 106.1 (2006): 38-43.
6. Bagchi A., et al. “A complete review on Parthenium hysterophorus Linn”. International Journal of Recent Advances in Pharmaceutical Research1 (2016): 42-49.
7. Berry MI. “Feverfew faces the future”. Pharmaceutical Journal10 (1984): 611-614.
8. Farnsworth NR. “Biological and phytochemical screening of plants”. Journal of Pharmaceutical Sciences 55 (1966): 225-276.
9. Kumar D and Dhobi M. “Screening of antianxiety and antioxidant profile of stems and leaves of blue variety of Clitoria ternatea L”. Indian Journal of Pharmaceutical Sciences6 (2017): 1022-1025.
10. Scheffer WC. “Statistics for the Biological Sciences”. Philippines: Addison-Wesley Publishing Company (1980): 121-41.

Citation

Citation: Devinder Kumar Maheshwari., et al. “Antioxidant Activity Investigation on Various Extracts of Parthenium hysterophorus Aerial Parts". Acta Scientific Pharmacology 3.11 (2022): 02-06.

Copyright

Copyright: © 2022 Devinder Kumar Maheshwari ., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.