Akhila TR¹*, Aswathy Bennit¹, Jitha Raj¹, Nizamudheen Nasar Kovvaprath¹ and Sujith S Nair²

¹Doctor of Pharmacy Intern, Crescent College of Pharmaceutical Sciences, Kerala University of Health Sciences, India
²Professor, Crescent College of Pharmaceutical Sciences, Kannur, Kerala, India

*Corresponding Author: Akhila TR, Doctor of Pharmacy Intern, Crescent College of Pharmaceutical Sciences, Kerala University of Health Sciences, India.

Received: June 20, 2022 Published: August 08, 2022

Abstract

The aim of study is to assess quality of life, drug-drug interaction and associated complication among diabetic patient in tertiary care hospital.

Materials and Methods: A Cross sectional study of six month duration was conducted. Data collected were documented, analysed and entered into Microsoft Excel. Statistical analysis was done by using Microsoft Excel.

Results: 120 patients were included in our study and among them 65 were males and 55 were females. The overall mean score of QoL in diabetic patients was 55.32, indicating a moderate to low QoL in them. From the total drugs prescribed, 143 interactions were found out and among this pharmacodynamic interactions (58.3%) were found to be more than pharmacokinetic interactions (45.8%). Most frequent complication was found to be hypertension (92.5%), followed by retinopathy (41.6%), CAD (39.1%), nephropathy (24.1%), foot ulcer (15.8%), neuropathy (15%) and stroke (9.16%).

Conclusion: Our study highlights the quality of life in Diabetic patient. The occurrence of Type 2 diabetes was more in case of males than female. Smoking is a risk factor for type 2 diabetes. Our study shows that the type 2 diabetes patients have low to moderate QoL. Majority of the patients had hypertension associated as complication.

Keywords: Type 2 Diabetes Mellitus; Quality of Life (QOL); WHOQOL-BREF Questionnaire; Pharmacokinetics; Pharmacodynamics

References

1. Saher Mahmood Jwad and HawraaYousif AL-Fatlawi. “The Effect of Diabetes on the Possessions of Blood and Vessels”. Journal of Advances in Pharmacy Practices1 (2022): 15-20.
2. Najjar ZSR., et al. “Assessment of 1.25 (OH). 2D3 levels and nephropathy stages in adult male patients with type-2 diabetes mellitus”. Journal of Critical Review13 (2020): 1667-1674.
3. Sura Essam Mohammed Reda., et al. “Biomaterials and Green Chemical Compounds and their Health Effect”. Journal of Pharma and Drug Regulatory Affairs1 (2022): 50-58.
4. Saher Mahmood Jwad and HawraaYousif AL-Fatlawi. “Diabetic Nephropathy and Its Effect on the Physiological Factors of The body”. Trends in Pharmaceuticals and Nanotechnology1 (2022): 24-30.
5. Israa Majid Neamah and Saher Mahmood Jwad. “Chronic Complications of Diabetes and their Impact on the Patient”. Journal of Advances in Bio-pharmaceutics and Pharmacovigilance1 (2022): 31-35.
6. Saher Mahmood Jwad and Israa Majid Neamah. “Hormonal and Genetic Influence of Diabetes Mellitus”. Journal of Pharmaceutical Quality Assurance and Quality Control 1 (2022): 22-26.

Citation

Citation: Akhila TR. “Assessment of Quality of Life, Drug-drug Interactions and Associated Complications Among Diabetic Patient in a Tertiary Care Hospital". Acta Scientific Pharmacology 3.9 (2022): 03-07.

Copyright

Copyright: © 2022 Akhila TR. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.