Sadhana Raut*, Poonam Shende, Nupur Gargate and Harshad Kapare

¹Department of Pharmaceutical Chemistry, Sinhgad College of Pharmacy, Vadgaon (bk), Pune, Maharashtra, India
²Department of Pharmaceutics, Dr.D. Y. Patil Pharmaceutical Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, Maharashtra, India

*Corresponding Author: Sadhana Raut, Department of Pharmaceutical Chemistry, Sinhgad College of Pharmacy, Vadgaon (bk), Pune, Maharashtra, India.

Received: June 06, 2022 Published: September 24, 2022

Abstract

Tabernaemontana divaricata is a shrub commonly found in many parts of the world. Flowers of the plant have a common ‘pinwheel’ shape, giving it the vernacular name “pinwheel flower”. This plant is highly rich in alkaloids like Conophylline, Isovoacristine, α-amyrin acetate, β-amyrin acetate etc. Gas chromatography-mass spectrophotometry also revealed that it contains chemical compounds like vitamin D, vitamin A aldehyde, vitamin E, phytol and many more. Due to the presence of chemical constituents like alkaloid and non-alkaloids, Tabernaemontana divaricata is used to treat various diseases. It has also been proved that the plant has antioxidant, anti-inflammatory, anti-tumour, anti-microbial and wound healing properties. Studies have found the plant extract to inhibit anticholinesterase enzyme, which makes it a potential drug in the treatment of Alzheimer’s disease and Myasthenia gravis. In the current review article, we have presented the extraction, standardization, phytochemical analysis, optimization techniques, pharmacological activities of Tabernaemontana divaricata plant. 

Keywords: Tabernaemontana divaricate; Extraction; Phytochemical; Standardization of Extract; Pharmacological Activities

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Citation

Citation: Sadhana Raut., et al. “Pharmacognostic and Pharmacological Aspects on Tabernaemontana divaricata Plant". Acta Scientific Pharmacology 3.10 (2022): 22-34.

Copyright

Copyright: © 2022 Sadhana Raut., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.