A Review on Endocrine Disrupting Chemicals
Jampala Rajkumar1*, RK Sreelakshmi2, Vineesha2 and Vuppu Shalini2
1Vaageswari College of Pharmacy (Affiliated to JNTUH), Karimnagar, Telangana, India
2Geethanjali College of Pharmacy, Malkajgiri, Telangana, India
*Corresponding Author: Jampala Rajkumar, H.O.D, Industrial Pharmacy, Department of Pharmaceutics, Vaageswari College of Pharmacy (Affiliated to JNTUH), Karimnagar, Telangana, India.
January 17, 2022 Published: January 28, 2022
The hormone biosynthesis, metabolism, or function, are deviated from normal homeostatic control or reproduction due to Endocrine-disrupting chemicals which are present in food, consumer products and our surrounding environment. We offer data that endocrine disruptors show consequences in reproduction system of both male and female, many types of cancer like prostate cancer, and also disease related to Neuroendocrinology which are stated in Scientific Statement of The Endocrine Society. EDCs is a major public health concern as per the epidemiological investigations and also clinical observations in humans. The mechanism of EDC involves different kinds of pathways, which includes peroxisome proliferator-activated receptor, Thyroid, estrogenic, anti-androgenic, and many other actions through receptors on nucleus or neurotransmitters, enzymes etc. Humans and wildlife animals can also be used as models in many other pathways. Furthermore, EDCs encompasses a wide range of compounds, including oregano chlorinated pesticides and industrial chemicals, plastics and plasticizers, fuels, and a variety of other chemicals found in the environment or in common use.
Keywords: Endocrine Systems; Endocrine Disruptors; Affect the Humans and Wildlife; Avoid Using Plastic Bottles; Metals; Pesticides; Fertilizers
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