Acta Scientific Pharmacology

Opinion Volume 3 Issue 1

Active Role of Secondary Metabolites in Pharmacology

PF Steffi*

Assistant Professor, PG and Research Department of Microbiology, Cauvery College for Women (Autonomous), Tamil Nadu, India

*Corresponding Author: PF Steffi, Assistant Professor, PG and Research Department of Microbiology, Cauvery College for Women (Autonomous), Tamil Nadu, India.

Received: October 22, 2021; Published: December 01, 2021


Secondary metabolites have played an important role in possessing various biological effects, which included antibiotic, antifungal and antiviral [1,2]. They provide basic knowledge of scientific use of herbs in the traditional medicine in many of the prehistoric communities [3]. These metabolites protect plants from various pathogens [4]. Some of the example for secondary metabolites are toxins, gibberellins, alkaloids and antibiotics [5]. Plant chemistry has an important role in therapeutic uses of herbs [6]. A virtuous knowledge about various chemical composition of plants will leads to better understanding of its possible medicinal value [7]. Contemporary chemistry plays primary role in basic life functions such as respiration, cell division, growth, storage and reproduction [8]. They include the components of processes such as Krebs or citric acid cycle, glycolysis, photosynthesis and associated pathways [9,10].


  1. Acquaviva R., et al. “Protocatechuic Acid, a Simple Plant Secondary Metabolite, Induced Apoptosis by Promoting Oxidative Stress through HO-1 Downregulation and p21 Upregulation in Colon Cancer Cells”. Biomolecules 10 (2021).
  2. Bobek J., et al. “6S-Like scr3559 RNA Affects Development and Antibiotic Production in Streptomyces coelicolor”. Microorganisms10 (2021).
  3. Charria-Giron E., et al. “Evaluation of the Antibacterial Activity of Crude Extracts Obtained From Cultivation of Native Endophytic Fungi Belonging to a Tropical Montane Rainforest in Colombia”. Frontiers in Microbiology 12 (2021): 716523.
  4. Cimmino A., et al. “Phenazine-1-Carboxylic Acid (PCA), Produced for the First Time as an Antifungal Metabolite by Truncatella angustata, a Causal Agent of Grapevine Trunk Diseases (GTDs) in Iran”. Journal of Agricultural and Food Chemistry 41 (2021): 12143-12147.
  5. Dou M., et al. “Genome Sequence Resource for Colletotrichum viniferum, the cause of grapevine ripe rot in China”. Molecular Plant-Microbe Interactions (2021).
  6. Fang L., et al. “Characterization of embryo and protocorm development of Paphiopedilum spicerianum”. Plant Physiology and Biochemistry 167 (2021): 1024-1034.
  7. Gonzalez-Quinonez N., et al. “The Modulation of SCO2730/31 Copper Chaperone/Transporter Orthologue Expression Enhances Secondary Metabolism in Streptomycetes”. International Journal of Molecular Sciences 18 (2021).
  8. Herrera R., et al. “In-vitro Chemopreventive Potential of a Chromone from Bomarea setacea (ALSTROEMERIACEAE) against Colorectal Cancer”. Iranian Journal of Pharmaceutical Research 2 (2021): 254-267.
  9. Jeong Y., et al. “Enhanced Large-Scale Production of Hahella chejuensis-Derived Prodigiosin and Evaluation of Its Bioactivity”. Journal of Microbiolog and Biotechnology 12 (2021).
  10. Witte TE., et al. “A metabolomic study of vegetative incompatibility in Cryphonectria parasitica”. Fungal Genetics and Biology 157 (2021): 103633.


Citation: PF Steffi. “Active Role of Secondary Metabolites in Pharmacology". Acta Scientific Pharmacology 3.1 (2022): 01-02.


Copyright: © 2022 PF Steffi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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