A Case Report of Iloperidone-induced Sleep-related Eating Disorder
Hani Raoul Khouzam*
Department of Psychiatry, Sacramento VA Medical Center and UC Davis Health, Sacramento, California, USA
*Corresponding Author: Hani Raoul Khouzam, MD;MPH. Staff Psychiatrist Department of Psychiatry, Sacramento VA Medical Center Clinical professor of Psychiatry and Medicine, UC Davis Health, Sacramento, California USA.
Received:
August 21, 2021; Published: August 30, 2021
Abstract
Sleep-related eating disorder is a Non-Rapid Eye Movement Sleep Arousal Disorders characterized by recurrent episodes of nocturnal eating or drinking after an arousal from the Non-Rapid Eye Movement (NREM) sleep stage. Several medications, including atypical antipsychotics, have been reported to induce sleep-related eating disorder. This case report illustrates the development of sleep -related eating disorder during treatment with the atypical antipsychotic Iloperidone. It also reviews Iloperidone core mechanisms of action of and propose a possible link between its effects on 5-hydroxytryptamine-2A and 2C (5-HT2A) and (5-HT2C) neuroreceptors and the development of Sleep-related eating disorder.
Keywords: Schizophrenia; Sleep-related Eating Disorder; Atypical Antipsychotics; Iloperidone; Treatment
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