Acta Scientific Pharmacology

Research Article Volume 2 Issue 9

Study of Lipids and Some Biologically Active Compounds from the Seeds of Apricot Growing in Georgia

Bela Kikalishvili*, Tsisana Sulakvelidze, Malkhaz Getia, Mariam Malania and Durmishkhan Turabelidze

Iovel Kutateladze Institute of Pharmacochemistry of Tbilisi State Medical University, Tbilisi, Georgia

*Corresponding Author: Iovel Kutateladze Institute of Pharmacochemistry of Tbilisi State Medical University, Tbilisi, Georgia

Received: August 03, 2021; Published: August 26, 2021


The aim of the present paper is to study the seeds of Apricot growing in Georgia (East Georgia, Kakheti Region) for the content of lipids and some biologically active compounds to use them in medicine, pharmacy, perfumery and cosmetology. The sum of neutral (N/L) and Polar lipids (P/L) from Apricot (Armeniaca vulgaris Mill) seeds were respectively obtained by using Hexane and chloroform-methanol mixture (2:1) extraction. Saturated, mono- and poly-unsaturated fatty acids were identified in some of the neutral lipids by Gas Chromatography combined with Mass Spectrometry. Were identified following acids: hexadecane (6.09%), hexadecene (1.68%), octadecane (2.25%), 9-octadecene (74.09%), eicosane (0.27%), eicosene (0.66%), tetracosane (0.13%) and hexacosane (0.09%). Hexadecane acid is dominant saturated acid (6.09%) and 9-octadecene acid is dominant unsaturated acid (74%). The sum of polar lipids is 1,46%. The content of carotenoids 4.7 mg%. Were identified 6 amino acids: histidine, asparagine, serine, alanine, valine and phenylalanine. Experimental pharmacological studies suggest, that Apricot (Armeniaca vulgaris Mill.) seed oil has a moderately pronounced anti-inflammatory, wound-healing and gastro protective activities.

Keywords: Lipid; Fatty Acid; Phospholipid


  1. Shipov AN., et al. “Vegetable oils and oil extracts”. Moscow. Russian doctor (2004): 119.
  2. Nikonov GK and Manuilov BM. “Fundamentals of modern pharmacotherapy”. Moscow, Medicine, (2005): 107.
  3. Kikalishvili B., et al. “Study of lipid composition of some plants growing in Georgia. Iovel Kutateladze Institute of Pharmacochemistry of Tbilisi Medical University”. International Academy Journal Web of Scholar33 (2019).
  4. Gagnidze R. “Vascular plants of Georgia, a nomenclatural checkligt”. Tbilisi (2005): 96-97.
  5. Shantser IA. “Plants of the moderate zone of European Russia”. Moscow (2007): 469.
  6. Rashid F., et al. “Flavonoid glycosides from Prunus armeniaca and the antibacterial activity of a crude extract”. Archives of Pharmacal Research 30 (2007): 932-937.
  7. Guclu K., et al. “Antioxidant capacity of fresh, sun- and sulphited-dried Malatya apricot (Prunus armeniaca) assayed by CUPRAC, ABTS/TEAC and folin methods”. International Journal of Food Science and Technology 1 (2006): 76-85.
  8. Karapetyan TD., et al. “In vitro antimicrobial activity of dried and fresh leaf extracts of old and young apricot trees (Prunus armeniaca)”. The New Armenian Medical Journal 4 (2011): 44-49.
  9. Morris Kates. Techniques of Lipidology. Isolation, Analysis and Identification of Lipids. M. (1975).
  10. Sponngord RY and Sun M. “Enhancement of an analytical method for the determination oils in viecine adsorbed formualtions”. Journal of Pharmaceutical and Biomedical Analysis 52 (2008): 554-564.
  11. Russian Parmacopeia XIII G method (quantitative determination of phosphorus with an Eiconogenin).
  12. ФС. 42-1052-76.
  13. British Pharmacopoeia volume V. London: The Stationery Office (2017): 202-203.
  14. Darrin L Smith. “Mass Spectrometry Applications in Forensic Science”. Encyclopedia of Analytical Chemistry, John Wiley and Sons Ltd, New York City (2010).
  15. Sukhija PS and Palmquist D. “Rapid method for determination of total fatty acid content and composition of feedstuffs and feces”. Journal of Agricultural and Food Chemistry 36 (1988): 1202-1206.
  16. Toshimasa T. “Modern Derivatization Methods for Separation Sciences”. (Copyright (c) 1999 John Wiley and Sons Ltd, Baffins Lane, Chichester, West Sussex PO19 IUD, England).


Citation: Bela Kikalishvili. “Study of Lipids and Some Biologically Active Compounds from the Seeds of Apricot Growing in Georgia".Acta Scientific Pharmacology 2.9 (2021): 24-27.


Copyright: © 2020 Bela Kikalishvili. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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