Abstract

 Globally, Approximately 70% of deaths from cancer occur in low- and middle-income countries due to the five leading behavior and dietary risks such are high body mass index, intakes of low fruit and vegetables lack of physical activities, tobacco and alcoholism. In low and middle income countries, about 25% of infectious diseases are hepatitis and human papilloma virus caused by cancer. Currently available chemo and radio therapies are have not only been able to cure this devastating disease but also cause many undesirable side effects. Medicinal plants has an important position in the drug discovery and many modern drugs have either origin in traditional medicine of different cultures, by accumulating information on the popular medicinal use of plants. There are well developed traditional medical systems with various herbal preparations which use to treat cancer through eliminating the carcinogen from the systems, blocking one or more steps in cancer development, retarding the further growth of cancer cells while minimizing side effects of chemotherapy. Therefore, there is an increasing demand for alternative plants based medicine for the treatment of various types of cancer due to low cost, lesser side effects, and long term effectiveness in chronic conditions. A. carambola plant has various pharmacological actions such as antioxidant, anti-inflammatory, hypotensive, hepatoprotective, anti-ulcer, antimicrobial and anthelmintic etc. Due to the presence of constituents such are alkyl phenols, benzoquinones, carotenoids, β- sitosterol, lupeol, anthraquinone glucoside and p-Anisaldehyde. Therefore this herbal could be developed valuable therapeutic agent for the cancer.

Keywords: Cancer; A carambola; Herbal; β-sitosterol; Sagadam; Star Fruit

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Citation

Citation: L Sarvananda and Amal D Premarathna. “Development, Characterization and Transdermal Delivery of Meloxicam Entrapped in Proniosomal Gel for the Treatment of Osteoarthritis".Acta Scientific Pharmacology 2.2 (2021):. 30-37

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Copyright: © 2021 L Sarvananda1* and Amal D Premarathna. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.