Acta Scientific Pharmacology

Short Communication Volume 2 Issue 1

Inflammation: Need for the Development of Novel Immunomodulators

Gundu H R Rao*

Emeritus Professor, Laboratory Medicine and Pathology, Director, Thrombosis Research, Lillehei Heart Institute, University of Minnesota, USA

*Corresponding Author: Gundu H R Rao, Emeritus Professor, Laboratory Medicine and Pathology, Director, Thrombosis Research, Lillehei Heart Institute, University of Minnesota, USA.

Received: December 02, 2020; Published: December 30, 2020

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  Inflammation refers to body’s process of fighting things that harm it, such as infections, injuries, and toxins, -to heal the injured tissues. When cellular and tissue damage occurs, the injured cells and tissues, release chemical messengers that trigger, a host of responses from the immune system. Common feature of inflammation includes redness, swelling, heat, pain, and loss of function. Any kid of infection can induce inflammation. On the other hand, a variety of food ingredients can also cause inflammation. Inflammation can be either short-lived (acute) or long lasting (chronic).

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References

  1. Brainard J. “Researchers face hurdles to evaluate, synthesize COVID-19 evidence at top speed”. Health, Scientific Community: Coronavirus Science (2020).
  2. Hojyo S., et al. “How COVID-19 induces cytokine storm with high mortality”. Inflammation and Regeneration 40 (2020): 37.
  3. Sinha P., et al. “Is a “Cytokine Storm” Relevant to COVID-19?” JAMA Internal Medicine9 (2020): 1152-1154.
  4. Yang Y., et al. “Exuberant elevation of IP-10, MCP-3, and IL-Ira during SARS-CoV-2 infection is associates with disease severity and fatal outcome”. medRxiv (2020).
  5. Zuo Yu., et al. “Neutrophil extracellular traps in COVID-19”. JCI Insight11 (2020): e138999.
  6. Zuo Y., et al. “Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19”. Science Translational Medicine (2020).
  7. Iannaccone G., et al. “Weathering the Cytokine Storm in COVID-19: Therapeutic Implications”. Cardiorenal Medicine 10 (2020): 277-287.
  8. Valenzuela O., et al. “First report of Tocilizumab in a cohort of Latin American patients hospitalized for severe COVID-19 pneumonia”. Frontiers in Medicine 16 (2020).
  9. “Dexamethasone in the management of COVID-19”. BMJ 37 (2020): 0m2648.
  10. Shuangli Mi., et al. “Circulating Micro RNAs as biomarkers for inflammatory Diseases”. MicroRNA1 (2013): 64-72.
  11. Iskanda HN and Ciobra MA. “Biomarkers in inflammatory bowel disease: current practices and recent advances”. Translational Research 4 (2012): 313-325.
  12. Xchonauen K., et al. “Circulating and fecal microRNAs as biomarkers for inflammatory bowel disease”. Inflammatory Bowel Disease 7 (2018): 1547-1557.
  13. Tan C., et al. “C-reactive proteins correlates with computed tomographic findings and predicts severe COVID-10 early”. Journal of Medical Virology7 (2020): 856-862.
  14. Zhang L., et al. “D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19”. Journal of Thrombosis and Haemostasis 6 (2020): 1324-1329.
  15. Ye W., et al. “Dynamic changes of D-dimer and neutrophil-lymphocyte ratio as prognostic biomarkers in COVID-19”. Respiratory Research 169 (2020).
  16. Mueller AL., et al. “Why does COVID-19 disproportionately affect older people?” Aging (Albany NY)10 (2020): 9959-9981.

 

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Citation

Citation: Gundu H R Rao. “Inflammation: Need for the Development of Novel Immunomodulators".Acta Scientific Pharmacology 2.1 (2021): 05-09.




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Acceptance rate36%
Acceptance to publication20-30 days

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