Acta Scientific Pharmacology

Research Article Volume 1 Issue 11

A Study of Clinical Presentation and Outcome of Patients with Acute Kidney Injury in a Tertiary Care Hospital

Sanjeeiv Krishnan CV1*, Candy Friyola A1, Mariraj I2, Jagadeesan M3, Prasanna Karthik S3, Kannan R4, Magesh Kumar S5 and Sanjeev V Nair3

1Postgraduate, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India
2Assistant Professor, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India
3Associate Professor, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India
4Chief, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India
5Head of Department, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India

*Corresponding Author: Sanjeeiv Krishnan CV, Postgraduate, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India.

Received: October 14, 2020; Published: October 30, 2020

×

Abstract

  This study was done to study the clinical, etiological profile, identification, classification and to study the impact and outcome of acute kidney injury. By convenient sampling patients were invited to take part in this study. All patients with clinical and biochemical evidence of acute kidney injury according to AKI NETWORK criteria were included. The patients were screened if he/she satisfied the eligibility criteria. The results of the analysis were validated statistically. It was found that the incidence of AKI was more in males as compared to females and it was maximum in the age group of 40-60 years. Alcoholics and smokers were at a higher risk of AKI. Fever was found to be the most common cause of AKI followed by obstruction, sepsis, congestive cardiac failure, poisoning, cerebrovascular accident, chronic liver disease, malaria and drug abuse. Patients with AKIN stage 3 were more likely to go for dialysis than stages 1 and 2. Ultrasound finding was normal in many patients (73.6%) followed by renal calculi (8.3%), carcinoma (4.2%), HUN (1.4%), ascites (6.9%) and cystitis (5.6%). A higher proportion of patients were found to have deranged liver enzymes (increased OT - 83.3%) as compared to normal (16.7%). Patients prone for AKI with hyponatremia is around 37.5% and those with normal sodium value are 62.5%. Most patients were managed conservatively (88.9%) and a few were taken up for dialysis (11.1%). The survival rate was 98.6% and mortality rate was 1.4%.

Keywords: Acute Kidney Injury; AKI; Clinical Profile; Etiological Profile

×

References

  1. Eswarappa M., et al. “Spectrum of acute kidney injury in critically ill patients: A single center study from South India”. Indian Journal of Nephrology5 (2014): 280.
  2. Ranganatha M. “Study of causes and prognosis of acute kidney injury (AKI) in tertiary care institute”. International Journal of Advances in Medicine4 (2017): 1165.
  3. Kapadia MP., et al. “A study of clinical profile of patients with acute kidney injury in a tertiary care centre”. International Journal of Advances in Scientific Research8 (2016): 160-166.
  4. Mataloun SE., et al. “Incidence, risk factors and prognostic factors of acute renal failure in patients admitted to an intensive care unit”. Brazilian Journal of Medical and Biological Research10 (2006): 1339-1347.
  5. Prakash J., et al. “Acute renal failure in the intensive care unit”. The Journal of the Association of Physicians of India 54 (2006): 784-788.
  6. Wiedermann CJ and Joannidis M. “Nephroprotective potential of human albumin infusion: a narrative review”. Gastroenterology Research and Practice (2015).
  7. Frenette AJ., et al. “Albumin administration is associated with acute kidney injury in cardiac surgery: a propensity score analysis”. Critical Care6 (2014): 602.
  8. Ostermann M., et al. “Correlation between the AKI classification and outcome”. Critical Care6 (2008): R144.
  9. Mehta RL., et al. “Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury”. Critical Care2 (2007): R31.
  10. Bellomo R., et al. “Acute renal failure: time for consensus”. Intensive Care Medicine11 (2001): 1685-1688.
  11. Wijewickrama ES., et al. “Incidences and clinical outcomes of acute kidney injury in ICU: a prospective observational study in Sri Lanka”. BMC Research Notes1 (2014): 305.
  12. Krishnamurthy S., et al. “Incidence and etiology of acute kidney injury in southern India”. The Indian Journal of Pediatrics3 (2013): 183-189.
  13. Pereira M., et al. “Acute kidney injury in patients with severe sepsis or septic shock: a comparison between the ‘Risk, Injury, Failure, Loss of kidney function, End-stage kidney disease’ (RIFLE), Acute Kidney Injury Network (AKIN) and Kidney Disease: Improving Global Outcomes (KDIGO) classifications”. Clinical Kidney Journal3 (2016): 332-340.
  14. Suh SH., et al. “Acute kidney injury in patients with sepsis and septic shock: risk factors and clinical outcomes”. Yonsei Medical Journal4 (2013): 965-972.
  15. Wiedermann CJ., et al. “Causal relationship between hypoalbuminemia and acute kidney injury”. World Journal of Nephrology4 (2017): 176.

 

×

Citation

Citation: Sanjeeiv Krishnan CV., et al. “A Study of Clinical Presentation and Outcome of Patients with Acute Kidney Injury in a Tertiary Care Hospital".Acta Scientific Pharmacology 1.11 (2020): 27-31.




Metrics

Acceptance rate36%
Acceptance to publication20-30 days

Indexed In


News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is December 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"

Contact US