Acta Scientific Pharmacology

Research Article Volume 1 Issue 11

A Study of Clinical Presentation and Outcome of Patients with Acute Kidney Injury in a Tertiary Care Hospital

Sanjeeiv Krishnan CV1*, Candy Friyola A1, Mariraj I2, Jagadeesan M3, Prasanna Karthik S3, Kannan R4, Magesh Kumar S5 and Sanjeev V Nair3

1Postgraduate, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India
2Assistant Professor, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India
3Associate Professor, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India
4Chief, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India
5Head of Department, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India

*Corresponding Author: Sanjeeiv Krishnan CV, Postgraduate, Department of General Medicine, Saveetha Medical College and Hospital, SIMATS, Thandalam, Chennai, India.

Received: October 14, 2020; Published: October 30, 2020

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Abstract

  This study was done to study the clinical, etiological profile, identification, classification and to study the impact and outcome of acute kidney injury. By convenient sampling patients were invited to take part in this study. All patients with clinical and biochemical evidence of acute kidney injury according to AKI NETWORK criteria were included. The patients were screened if he/she satisfied the eligibility criteria. The results of the analysis were validated statistically. It was found that the incidence of AKI was more in males as compared to females and it was maximum in the age group of 40-60 years. Alcoholics and smokers were at a higher risk of AKI. Fever was found to be the most common cause of AKI followed by obstruction, sepsis, congestive cardiac failure, poisoning, cerebrovascular accident, chronic liver disease, malaria and drug abuse. Patients with AKIN stage 3 were more likely to go for dialysis than stages 1 and 2. Ultrasound finding was normal in many patients (73.6%) followed by renal calculi (8.3%), carcinoma (4.2%), HUN (1.4%), ascites (6.9%) and cystitis (5.6%). A higher proportion of patients were found to have deranged liver enzymes (increased OT - 83.3%) as compared to normal (16.7%). Patients prone for AKI with hyponatremia is around 37.5% and those with normal sodium value are 62.5%. Most patients were managed conservatively (88.9%) and a few were taken up for dialysis (11.1%). The survival rate was 98.6% and mortality rate was 1.4%.

Keywords: Acute Kidney Injury; AKI; Clinical Profile; Etiological Profile

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References

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Citation

Citation: Sanjeeiv Krishnan CV., et al. “A Study of Clinical Presentation and Outcome of Patients with Acute Kidney Injury in a Tertiary Care Hospital".Acta Scientific Pharmacology 1.11 (2020): 27-31.




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