Abstract

  Now a days trends in development of mucoadhesive drug delivery system (MDDS) is particularly appropriate than oral control release, for getting local systematic delivery of drugs in gastro intestinal tract (GIT) for an extended interval of time at a predetermined rate. The mucoadhesive system have a significant impact that draws further attention to potential benefits like improved bioavailability of therapeutic agents, extensive drug residence time at the site of administration and a comparatively faster drug uptake into the systemic circulation. The drug release from mucoadhesive multiparticulates is contingent on several types of factors comprising carrier need to produce the multiparticles and quantity of medication drug contained in them. Mucoadhesion is characterized by selected theories and mechanisms. Various strategies emergent in mucoadhesive multiparticulate drug delivery system (MMDDS) by in-vitro as well as ex-vivo description and characterization are also critically discussed. Apart from these, the primary focus during this review is to highlight current patents, clinical status, and regulatory policy for enhancement of mucoadhesive multi-particulate drug delivery system in the present scenario.

Keywords: Mucoadhesive Drug Delivery System; Therapeutic Agents; Mucoadhesion

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Citation

Citation: Chinmaya Keshari Sahoo and Amiyakanta Mishra. “Mucoadhesive Microcapsules: A Review".Acta Scientific Pharmacology 1.11 (2020): 16-23.

Copyright

Copyright: © 2020 Chinmaya Keshari Sahoo and Amiyakanta Mishra. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.