Abstract

  Piperine is the principle alkaloid present in Piper nigrum and Piper longum species of black pepper which has wide range of pharmacological activities. Piperine was used in the preparation of traditional medicines as well as in modern medicine. Piperine was found to have many pharmacological actions such as analgesic, anti-inflammatory, antioxidant, antitumor, anti-epileptic, anti-rheumatic, hepatoprotective, immunomodulatory effects and so on, in various animal models. The piperine use has been limited due to its low aqueous solubility. For the formulation of a wide range of poorly aqueous soluble drugs, solid lipid nanoparticles are used because of their biodegradable and biocompatible properties and low toxicity. Solid lipid nanoparticles possess unique properties like small size, large surface area and high drug loading ability. The solubility of piperine can be enhanced by formulating them as solid lipid nanoparticles by using different preparation techniques and it can be effectively used for its diverse applications as mentioned earlier.

Keywords: Anti-Oxidant Activity; Bio Enhancing Activity; Anti-Tumor Activity; Anti-inflammatory Effect

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Citation

Citation: M Ravindra Babu., et al. “Emerging Diverse Medicinal Properties of Piperine: A Review".Acta Scientific Pharmacology 1.10 (2020): 30-35.

Copyright

Copyright: © 2020 M Ravindra Babu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.