Chandrajeet Kumar Yadav1*, Kamal Poudel1, Pinki Yadav2 and Roshan Mehta1
1Department of Pharmacology, Universal College of Medical Sciences, Bhairahawa,
2Universal College of Medical Sciences, Bhairahawa, Nepal
*Corresponding Author:Chandrajeet Kumar Yadav, Department of Pharmacology, Universal College of Medical Sciences, Bhairahawa, Nepal.
Received: April 09, 2020; Published: August 12, 2020
The present study was designed to study the anti-depressant activity of the seeds extract of Zanthoxylum armatum using forced swim test and tail suspension test on swiss albino mice. The anti-depressant activity of the seeds of Zanthoxylum armatum was assessed using Chronic Unpredictable Mild-Stress (CUMS) induced depression in mice. The animals were treated with the Methanolic extract of seeds of Zanthoxylum armatum orally at two doses of 100, 200 mg/kg body weight for eight days after (CUMS) induced depression in mice. These results demonstrate that Methanolic extract of Zanthoxylum armatum has got anti-depressant potential.
Keywords: Zanthoxylum armatum; Methanolic Extracts; Anti-depressant Activity; Imipramine
Citation: Chandrajeet Kumar Yadav., et al. “Anti-depressant Activity of the Seeds of Zanthoxylum armatum on Swiss Albino Mice".Acta Scientific Pharmacology 1.9 (2020): 03-10.
Copyright: © 2020 Chandrajeet Kumar Yadav., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.