Acta Scientific Pharmacology

Research Article Volume 1 Issue 8

Pharmacognostic Study and Evaluation of the Antioxidant Activity of Chuquiraga jussieui J.F. Gmel (Asteraceae)

Carlos E Viteri-Poveda3, Yamilet I Gutiérrez-Gaitén3, Gabriela Carrillo-Lavid3 and Migdalia Miranda-Martíez3*

1Faculty of Chemical Sciences, Guayaquil University, Ecuador
2Department of Pharmacy, Institute of Pharmacy and Food, Havana University, Coronela, Lisa, Havana, Cuba
3Department of Chemical and Environmental Sciences, Faculty of Natural Sciences and Mathematic, ESPOL Polytechnic University, Ecuador

*Corresponding Author: Migdalia Miranda-Martínez, Department of Chemical and Environmental Sciences, Faculty of Natural Sciences and Mathematic, ESPOL Polytechnic University, Ecuador.

Received: June 23, 2020; Published: July 30, 2020

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Abstract

Chuquiraga jussieui J.F. Gmel has traditionally been used for its therapeutic virtues, nevertheless, scientific studies are scarce. The pharmacognostic, phytochemical evaluation and antioxidant activity of flowers, leaves, stems and roots of the species are presented. Some physicochemical parameters were determined for the powdered drugs and the hydroalcoholic extracts (30% ethanol), phytochemical screening was performed, and phenols were quantified by Folin-Ciocalteu and flavonoids by the aluminum-chloride method. Antioxidant activity was evaluated by the FRAP, DPPH and ABTS tests. Significant differences were found in the physicochemical parameters notably substances soluble in 30% ethanol, total solids, phenols and flavonoids were higher for leaves and flowers. All the extracts showed ferro-reducing activity, although greater in leaves and flowers. All extracts demonstrated radical-scavenging antioxidant activity by the DPPH and ABTS assays, highlighting the extracts of leaves (IC50 40.57 μg/mL, DPPH and 242.2 μg/mL, ABTS) and flowers (IC50 40.60 μg/mL, DPPH and 286.0 μg/mL, ABTS) for having more activity. The pharmacognostic study can contribute to the development of quality control standards of the species and the antioxidant potential demonstrated in the extracts is associated with the active substances present in them.

Keywords: Chuquiragua; Phenolic Compound; Flavonoids, Physicochemical Parameters Antioxidant Activity

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Citation

Citation: Viteri-Poveda., et al. “Pharmacognostic Study and Evaluation of the Antioxidant Activity of Chuquiraga jussieui J.F. Gmel (Asteraceae)". Acta Scientific Pharmacology 1.8 (2020): 03-14.




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