MK Prashanth1, TD Devaraj1, BK Jayanna1* and KP Roopa2
1Department of Chemistry, B. N. M. Institute of Technology, Bengaluru, India
2Department of Chemistry, Sapthagiri College of engineering, Bengaluru, India
*Corresponding Author: BK Jayanna, Professor and Head, Department of Chemistry, B. N. M. Institute of Technology, Bengaluru, India.
Received: March 28, 2020; Published: May 31, 2020
This work proposes a method for simple spectrophotometric determination of Lamotrigine (LMT) in presence of Risperidone (RSP) was accomplished using second derivative spectrophotometry. In the present method, neither a chromogenic reagent nor any other reagents are required. Excipients with drug molecule do not interfere with the determination. The Lamotrigine can be determined in the range of 1.0 -20 μg/mL. All other analytical parameters are established. The proposed method was more appropriate to the pharmaceutical formulation for the determination of Lamotrigine.
Keywords: Lamotrigine; Risperidone; Second Derivative Spectrophotometry
Citation: BK Jayanna., et al. "Derivative Spectrophotometric Method for Determination of Lamotrigine and Risperidone in Pharmaceutical Dosage Forms".Acta Scientific Pharmacology 1.6 (2020): 11-16.
Copyright: © 2020 BK Jayanna., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.