Abstract

  Chronic Obstructive Pulmonary Disease is a heterogeneous disease with various clinical presentations. It is a multicomponent disease with extra-pulmonary effects. The study was carried out to assess drug use and prescribing pattern by various medical practitioners in COPD patients with or without co-morbidity. The study was conducted at MMIMSR. In our prospective study analysis, a total of 80 COPD patients were selected randomly. Out of which, 20 patients were excluded from the study on the basis of the exclusion criteria, and remaining 60 patients fulfilling inclusion criteria were included. Among the total number of patients, Bi-therapy was prescribed predominantly (55%), followed by tritherapy (37%), least number of patients was prescribed monotherapy (8%) showed in table 6. The COPD patients included in the study were prescribed medications by various Medical Practitioners (A, B, C) among which, 28% patients were prescribed medications by A, 33% by B and 39% by C, In conclusion, maximum improvement in the symptoms of disease (CAT score) was found out with Bi-therapy (combination of Sympathomimetics and Xanthene derivatives), the Quality of life (SF36 Questionnaire score) seems to be improved with Bi-therapy (Combination of Anticholinergics and Xanthene derivatives) also, the severity of disease (Dyspnea score) found to be improved with Bi-therapy (Combination of Anticholinergics and Xanthene derivatives). Also, most of the Medical practitioners prescribed majorly Bi-therapy in COPD patients.

Keywords: Drug Utilization; COPD; Prescribing Pattern; Drugs; Tertiary Care

References

1. Vestbo Jorgen. “Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease”. Global Initiative for Chronic Obstructive Lung Disease, ATS Journal 4 (2013): 347-365.
2. Former L and Cooper CB “A review of the GOLD Guidelines for the diagnosis and treatment of patients with COPD”. International Journal of Clinical Practice 111 (2008): 1041-1742.
3. Peter J Barnes. “Emerging Pharmacotherapy’s for COPD”. Chest (2008): 134
4. Pirozzi C and Scholand MB. "Smoking cessation and environmental hygiene". Medical Clinics of North America 4 (2012): 849-867. 
5. Noehren TH. “Pulmonary emphysema, improved outlook in the management of patients”. JAMA (1962): 887-889.
6. Levine BE., et al. “The role of long-term continuous oxygen administration in patients with chronic airway obstruction with hypoxemia”. Annuals of International Medicine 66 (1967): 639-650. 
7. Petty TL., et al. “A comprehensive care program for chronic airway obstruction. Methods and preliminary evaluating of symptomatic and functional improvement”. Annuals of International Medicine 70 (1969): 1109-1120. 
8. Alex J Mackay., et al. “Usefulness of the Chronic Obstructive Pulmonary Disease Assessment Test to Evaluate Severity of COPD Exacerbations". American Journal of Respiratory and Critical Care Medicine 11 (2012): 1224.
9. Fletcher CM. “The clinical diagnosis of pulmonary emphysema—an experimental study”. Proceedings of the Royal Society of Medicine 45 (1952): 577-584.

Citation

Citation: Avinash Teli., et al. “A Study of Drug Utilization and Prescribing Patterns of Drugs in Chronic Obstructive Pulmonary Diseased Patients (IPD and OPD) in Tertiary Care Hospital”. Acta Scientific Pharmacology 1.3 (2020): 04-12.

Copyright

Copyright: © 2020 Avinash Teli., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.