Klebsiella pneumoniae is one of the commonest bacterial isolates in infectious respiratory tract conditions and also an important cause of infection in persons with an impaired immune system. It can spread rapidly between patients in healthcare settings and is a frequent cause of hospital outbreaks. The increasing prevalence of antimicrobial-resistant K. pneumoniae is a public health concern globally. However, data on this subject matter are scarce in the study area. This study was carried out to determine the prevalence and antimicrobial susceptibility pattern of K. pneumoniae isolated from sputum, causing respiratory tract infection in a tertiary care hospital in Kano, Kano State, Nigeria. A total of 150 sputum samples were collected and tested using standard microbiologic procedures. Antibiotic susceptibility test was by modified Kirby –Buaer disk diffusion method. Data were analysed using Open Epi Info statistical package version 2.0 and Chi-square test was used for statistical analysis.  The present study reveals 30% frequency of isolation of K. pneumoniae from sputum samples and their significance antibiotic resistance. Females and patients above 60 years of age were more affected by the infections. K. pneumoniae was found to be resistant to Cotrimoxazole and penicillin derivatives but most sensitive to Levofloxacin, Ciprofloxacin, Gentamicin and Ofloxacin.. There is need for increased enlightenment campaign about prevention/control of K. pneumoniae to checkmate the spread of associated infections, morbidity and mortality

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Citation

Citation: Ndaleh Wozerou Nghonjuyi., et al. “Prevalence and Antimicrobial Susceptibility Pattern of Klebsiella Pneumoniae in Sputum Samples of Patients Attending Aminu Kano Teaching Hospital of Kano State, Nigeria”. Acta Scientific Pharmacology 1.2 (2020): 07-11.

Copyright

Copyright: © 2020 Ada Ndaleh Wozerou Nghonjuyi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.