Keisuke Onoda*, Shunsuke Hatakenaka, Ryousuke Doi, Jumpei Kato, Tomihiro Wakamiya, Masahiro Indou, Kimihiro Nakahara, Tatsuya Tanaka, Takashi Agari, Takashi Sugawara, Kazuaki Shimoji, Eiichi Suehiro, Hiroshi Itokawa and Akira Matsuno

Department of Neurosurgery, International University of Health and Welfare, School of Medicine, Narita Hospital, Chiba, Japan

*Corresponding Author: Keisuke Onoda, Department of Neurosurgery, International University of Health and Welfare, School of Medicine, Narita Hospital, Chiba, Japan.

Received: January 02, 2026; Published: January 31,2026

Abstract

Traumatic brain injury (TBI) refers to an alteration in normal brain function resulting from an external force, such as a blow, jolt, or penetrating injury to the head. The severity of TBI ranges from mild to severe and is classified based on the degree of brain damage and associated clinical symptoms. Common causes include falls, motor vehicle collisions, sports-related injuries, and acts of violence

Background:Unruptured intracranial aneurysms (UIAs) generally exhibit slow growth, with rapid enlargement over a short period being uncommon.

Case Description: We report the case of a 69-year-old female in whom a 2-mm rt. middle cerebral artery aneurysm was detected routine brain screening. Follow-up magnetic resonance imaging (MRI) seven months later demonstrated enlargement to 5 mm with subtle hemorrhagic signal changes. Despite the recommendations for early intervention, the patient opted for continued observation. One month later, the patient was referred to our department. Owing to enlargement to 6 mm observed during three-dimensional computed tomography angiography (CTA), surgery was performed. The intraoperative findings revealed further enlargement to approximately 10 mm, and microsurgical clipping was successfully performed.

Conclusion: This case highlights the fact while UIAs rarely exhibit rapid growth over weeks or months, close interval growth and hemorrhagic imaging findings should prompt urgent reconsideration of management strategies.

Keywords: Unruptured Intracranial Aneurysm; Rapid Growth; Case Report; Microsurgical Clipping

References

1. Wiebers DO., et al. “Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment”. Lancet9378 (2003): 103-110.
2. Villablanca JP., et al. “Natural history of asymptomatic unruptured cerebral aneurysms evaluated at CT angiography: growth and rupture incidence and correlation with epidemiologic risk factors”. Radiology1 (2013): 269:258-265.
3. Sonobe M., et al. “Small unruptured intracranial aneurysm verification study: SUAVe study, Japan”. Stroke 9 (2010): 1969-1977.
4. Backes D., et al. “Growth of unruptured intracranial aneurysms: a systematic review”. Stroke 47 (2016): 951-957.
5. Frösen J., et al. “Saccular intracranial aneurysm: pathology and mechanisms”. Acta Neuropathologica6 (2012): 773-786.
6. Kataoka K., et al. “Structural fragility and inflammatory response of ruptured cerebral aneurysms”. Stroke7 (1999): 1396-1401.
7. Chalouhi N., et al. “Biology of intracranial aneurysms: role of inflammation”. Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism 9 (2012): 1659-1676.
8. Aoki T., et al. ”The development and the use of experimental animal models to study the underlying mechanisms of cerebral aneurysms”. Journal of Biomedicine and Biotechnology 2011 (2011): 535921.
9. Meng H., et al. “High wall shear stress or low wall shear stress? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture”. American Journal of Neuroradiology 35.7 (2014): 125-132.
10. Edjlali M., et al. “Intracranial aneurysm wall enhancement and its relationship with aneurysm instability”. Radiology 273 (2014): 536-542.

Citation

Citation: Keisuke Onoda., et al. “Rapid Growth of an Unruptured Intracranial Aneurysm Over a Short Period: A Case Report". Acta Scientific Neurology 9.2 (2026): 07-10.

Copyright

Copyright: © et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.