Zeinab Kone¹*, Dramane Coulibaly², Denahin Hilaire Hinnitondji Toffa³, Amadou Gallo Diop⁴ and Marie Moftah⁵

¹Neurologist, Neurology Department, Point G Teaching Hospital, Bamako, Mali
²Neurologist, Neurology Department, Luxembourg Teaching Hospital, Bamako Mali
³Neurologist, Université de, Montreal, Montréal, Canada
⁴Neurologist, Head Neurology, Department, Fann Teaching Hospital, Dakar, Senegal
⁵PHD Developpemental Biology, Alexandria University

*Corresponding Author:Zeinab Kone, Neurologist, Neurology Department, Point G Teaching Hospital, Bamako, Mali.

Received: May 06, 2025; Published: June 26, 2025

Abstract

Background: The priority given to thrombolysis (still inaccessible in our countries) should not make us forget other factors of aggression and/or aggravation in the management of strokes. So-called stress hyperglycemia, the result of oxidative stress, is implicated in the occurrence of a poor functional prognosis, and possibly higher mortality. Recent studies recommend 1.55 grams per liter (g/l) as the critical threshold, whereas in our department this threshold is 2 g/l. This study aims to determine the functional prognosis of an acute cerebral infarction associated with uncorrected hyperglycemia before the threshold value of 2g/l.

Method: Thus over a period of 3 months, we recruited patients who had had a Stroke within 24 hours and in whom we measured blood sugar on admission as well as monitored their functional outcomes by administering different evaluation scales of motor disability over a period of 6 weeks.

Results: In 70 patients of different sexes and of varying ages, 13 had blood sugar levels above 2g/l; 19 with blood sugar between 1.55 g/dl and 1.99 g/dl (therapeutic abstention group) and finally 38 with normal blood sugar (0.85 g/dl to 1.54 g/dl). On admission, the NIHSS score was higher for the therapeutic abstention group at 11.84. A poor evolution was also observed in the same group with worse scores at 6 weeks for the NIHSS at 10.21; for the Rankin’s scale at 3.47 and for the Barthel’s scale at 53.15. They also had a longer stay in hospital and greater mortality than the other two groups.

Conclusion: We believe that hyperglycemia should be normalized in the acute phase of stroke, despite fears of hypoglycemia when correcting it. With careful monitoring, we can follow the literature recommendations for the wellness of our patients.

Keywords: Hyperglycemia; Acute Stroke; Thrombolysis

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Citation

Citation: Zeinab Kone., et al. “Hyperglycemia in Acute Stroke".Acta Scientific Neurology 8.7 (2025): 22-39.

Copyright

Copyright: © 2025 Zeinab Kone., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.