Sanjo K John*, M Sacratis, N Shobana, V Sadeeshkumar and CJ Selvakumar

Resident, Department of Neurology, Coimbatore Medical College, Coimbatore, Tamil Nadu, India

*Corresponding Author: Sanjo K John, Resident, Department of Neurology, Coimbatore Medical College, Coimbatore, Tamil Nadu, India.

Received: June 26, 2024; Published: August 29, 2024

Abstract

Background: The presence of internal carotid artery (ICA) occlusion in patients presenting with acute ischemic stroke are still debatable. The prevalence of ICA occlusion in India is reported to be above 40%. Various management strategies are reported in the literature for ICA occlusion, with best medical therapy to be administrated urgently in order to prevent further worsening of the symptoms. This study reported the clinical profile, treatment, and outcome at discharge and at 6-month follow up in patients with symptomatic ICA occlusion.

Methodology: The study included 30 patients admitted in our institution during the study duration, with first ever acute ischemic stroke and with ICA occlusion of more than 50% identified through CV Doppler or MR angiogram. The neurological assessment and serum analysis were documented and the treatment outcome at discharge and at 6-month follow up assessed using modified Rankin scale. Spearman correlation analysis was performed to assess the relationship between the severity of occlusion and outcome in the patients recruited for the study.

Results: The mean age of the recruited patients was 55.20 ± 11.71 years, and consisting of 27 males and 3 females. The complete occlusion of the right ICA was reported in majority of the patients (26.6%), followed by 70% occlusion of the left ICA (16.6%). The mean modified Rankin score at the time of discharge was 2.77 ± 1.073, and at 6-month follow up was 1.40 ± 0.968. There was no relationship identified between the severity of ICA occlusion and outcome in the patients with symptomatic ICA occlusion.

Conclusion: The study concludes that the outcome of patients at the time of discharge or at 6-month follow up does not depend on the severity of ICA stenosis, suggesting the possibility of other factors influencing the outcome. The best medical therapy found to be effective in symptomatic patients with ICA occlusion, with no mortality or a recurrence of neurological symptoms reported during the study period.

 Keywords: Acute Ischemic Stroke; Internal Carotid Artery Occlusion; Modified Rankin Scale; Best Medical Therapy; Dual Antiplatelet Therapy

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Citation

Citation: Sanjo K John., et al. “Internal Carotid Artery Occlusion - Clinical Profile, Treatment, and Outcome; An Observational Study on Patients in a Tertiary Care Center”. Acta Scientific Neurology 7.9 (2024): 08-11.

Copyright

Copyright: © 2024 Sanjo K John., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.