Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Research Article Volume 7 Issue 7

Prevalence of Neurocysticercosis Infection Among HIV Individuals from a Tertiary Neurocare Center India

Shripad A Patil1*, Kruthika P2, Abhishek P3 and Netra M4

1Professor, Department of Neuromicrobiology, NIMHANS, Bangalore, India
2Microbiology, Assistant Professor, Department of Microbiology, Sri Ramachandra Medical College, Sri Ramachandra Institute of Higher Education and Research, Chennai India
3Medical Officer, Mysore, Karnataka, India
4Professor of Neurology NIMHANS, Bangalore, India

*Corresponding Author: Shripad A Patil, Professor, Department of Neuromicrobiology, NIMHANS, Bangalore, India.

Received: March 16, 2024; Published: June 27, 2024

Abstract

Neurocysticercosis (NCC) is the infection of central nervous system (CNS) caused by the cysticercal larvae of the parasite Taenia solium. NCC Accounts for 30% of all treatable epilepsy cases among endemic countries. Worldwide increase in the cases of HIV infections, has led to increase in the coinfection by various pathogens. The interactions between HIV and Taenia solium are not well defined. The present retrospective study has a total 92 cerebrospinal fluid (CSF) samples from HIV reactive patients which were subjected for anti cysticercal antibody assay by indigenously developed indirect ELISA. Twelve CSF samples showed reactivity for cysticercal antigens by ELISA.  The overall prevalence of Neurocysticercal infection among HIV infected individuals was 13.04% which is higher in comparison to other studies. Middle aged males were predominantly affected. There are very limited studies available in literature which focusses on the epidemiological, diagnostic and management guidelines on HIV/NCC coinfection. Further studies are needed to generate data from different centers on this neglected and co-infection group.

 Keywords: Central Nervous System; Enzyme Linked Immunosorbent Assay; Human Immunodeficiency Virus; Neurocysticercosis; Taenia Solium

References

  1. Jewell PD., et al. “Neurocysticercosis and HIV/AIDS co‐infection: A scoping review”. Tropical Medicine and International Health10 (2021): 1140-1152.
  2. HIV - World Health Organization (WHO).
  3. Garcia HH and Del Brutto OH. Cysticercosis Working Group in P. “Neurocysticercosis: updated concepts about an old disease”. The Lancet Neurology10 (2005): 653-661.
  4. Herrera Vazquez O., et al. “Neurocysticercosis and HIV Infection: what can we learn from the published literature?” Arquivos de Neuro-Psiquiatria 77 (2019): 357-365.
  5. Chang CC., et al. “HIV and co-infections”. Immunological Reviews 1 (2013): 114-142.
  6. Gams Massi D., et al. “Spectrum of central nervous system infections in a tertiary health care centre in Cameroon”. The Egyptian Journal of Neurology, Psychiatry and Neurosurgery1 (2022): 18.
  7. Patil SA., et al. “Comparative evaluation of dot blot and ELISA for the detection of anticysticercal antibodies in the cerebrospinal fluid for the immunodiagnosis of neurocysticercosis”. International Journal of Health Sciences and Research 2 (2015): 75-82.
  8. Jessurun J., et al. “The prevalence of invasive amebiasis is not increased in patients with AIDS”. AIDS (London, England) 3 (1992): 307-309.
  9. Moskowitz LB., et al. “The neuropathology of acquired immune deficiency syndrome”. Archives of Pathology and Laboratory Medicine11 (1948): 867-72.
  10. Benner CT., et al. “Association between HIV infection and the proportion of NCC lesions among patients with neurological disorders in the Eastern Cape Province, South Africa”. American Journal of Tropical Medicine and Hygiene 6.1 (2011): 29-30.
  11. Kumwenda JJ., et al. “Differential diagnosis of stroke in a setting of high HIV prevalence in Blantyre, Malawi”. Stroke; a Journal of Cerebral Circulation5 (2005): 960-964.
  12. Parija SC and Gireesh AR. “A serological study of cysticercosis in patients with HIV”. Revista do Instituto de Medicina Tropical de São Paulo 4 (2009): 185-189.
  13. Schmidt V., et al. “Association between Taenia solium infection and HIV/AIDS in northern Tanzania: a matched cross sectional-study”. Infectious Diseases of Poverty 1 (2016): 111.
  14. Noormahomed EV., et al. “A cross-sectional serological study of cysticercosis, schistosomiasis, toxocariasis and echinococcosis in HIV-1 infected people in Beira, Mozambique”. PLoS Neglected Tropical Diseases 9 (2014): e3121.
  15. Butala C., et al. “Neurocysticercosis: current perspectives on diagnosis and management”. Frontiers in Veterinary Science 8 (2021):
  16. Lozano R., et al. “Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010”. Lancet 9859 (2012): 2095-128.

Citation

Citation: Shripad A Patil., et al. “Prevalence of Neurocysticercosis Infection Among HIV Individuals from a Tertiary Neurocare Center India”. Acta Scientific Neurology 7.7 (2024): 57-60.

Copyright

Copyright: © 2024 Shripad A Patil., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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