Surasak Komonchan, Sahaphum Taemeeyapradit and Saharat Aungsumart*

Department of Neurology, Neurological Institute of Thailand, Bangkok, Thailand

*Corresponding Author: Saharat Aungusmart, Department of Neurology, Neurological Institute of Thailand, Bangkok, Thailand.

Received: February 29, 2024; Published: April 23, 2024

Abstract

Background: Transient ischemic attack (TIA) is a predisposing factor for ischemic stroke. This study aimed to identify an alternative prognostic indicator for predicting ischemic events after TIA. Red blood cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) have emerged as potential candidates.

Objective: This study aimed to determine the correlation between RDW and NLR and the risk of recurrent ischemic events in patients with TIA.

Methods: Patients hospitalized with a TIA diagnosis within 24 h from January 2015 to December 2022 were retrospectively analyzed for demographic and laboratory data. Recurrent ischemic events within 7 and 90 days were assessed by comparing RDW and NLR. Logistic regression was used to analyze the association between RDW and NLR and recurrent events.

Results: In total, 283 patients were included in this study. The RDW in patients with recurrent ischemic events within 7 days was 13.35, which was not significantly different from that in the non-ischemic group (13.7). NLRs were 2.03 and 2.24 for patients with TIA with and without recurrent events within 7 days, respectively. For the 90-day follow-up period, patients with TIA with recurrent ischemic events and those without ischemia in 90 days had RDWs of 13.55 and 13.7, respectively, which were not significantly different. The NLR in patients with TIA with recurrent ischemic events in 90 days was also not different from that of the non-ischemic group. The area under the receiver operating characteristic curve obtained from RDW or NLR did not demonstrate a correlation with recurrent ischemic stroke in patients with TIA at either 7 or 90 days.

Conclusions: RDW and NLR are not associated with the occurrence of recurrent ischemic events 7 and 90 days after TIA diagnosis.

 Keywords: Transient Ischaemic Attack; Red Blood Cell Distribution Width; TIA; RDW; Neutrophil-to-lymphocyte Ratio; NLR

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Citation

Citation: Surasak Komonchan., et al. “Association between Red Blood Cell Distribution Width and Neutrophil-to-lymphocyte Ratio and the Incidence of Recurrent Ischemic Events in Patients with Transient Ischemic Attack”. Acta Scientific Neurology 7.5 (2024): 19-27.

Copyright

Copyright: © 2024 Surasak Komonchan., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.