Rabha Elsahli* and Mohammed FG Elshukri

Benghazi University, Libya

*Corresponding Author: Rabha Elsahli, Benghazi University, Libya.

Received: November 21, 2023; Published: February 14, 2024

Abstract

Introduction: Stroke is the most common cause of seizures in the elderly, and seizures are among the most common neurologic sequelae of stroke. About 10% of all stroke patients experience seizures, from stroke onset until several years later.

Aim: To evaluate the frequency and predictive factors of early and late seizures after stroke. Methodology: A retrospective analysis (Cross-sectional study)

Data collection: Data was collected in pre-designed proforma subsequently, the data was entered into the computer. 

Data analysis: The results were analyzed using SPSS version 22 for Windows. 

Results: The study included 102patients with stroke, their mean age was70.1 ± 12.2years. Seizure was recorded in 45( 44.1%).Onset of seizure was early in 15.6% and late in 84.4%. History of ischemic heart disease was recorded in 39.2%of-patients. History of hypertension was positive in 79.4%, while diabetes was present in 69.6%. Hyperlipidemia was present in 51%. Almost the seizure was-recorded similar in all age groups, and it was-highest in age group(61-70 years) 48.5%,and lowest in >80 years, the difference-was not-statistically significant. Mean age of-patients-with seizure-was 68.7 ± 11.3, while mean age of patients without seizure was 71 ± 12.9years, the difference between the means was not statistically significant p=0.404 Seizure was recorded 43.5% of males and 45% of females, this difference was not significant. All-patients with seizure had history of hypertension. History of diabetes was recorded in77.8% 0f patients with seizure. Ischemic heart disease was present in 26.7% of patients with seizure. Ischemic heart disease-was-recorded-in100% of patients aged >80 years, and lowest was in age-group-51-60 years (18.8%),followed by-age-group, 61-70 years 24.2%,than ≤50 years was.33.3% and 71-80 years was 34.8%, these difference was statistically significant p –value was 0.0001.Ischemic heart disease was recorded in 44.1% of males and 36.8% of females, this difference was not statistically significant p = 0.621. Early onset of seizure was recorded in 11.7% of patients who had ischemic heart disease and 17.9% in patients not suffering ischemic heart disease, late onset was recorded in 83.3% of patients with ischemic heart disease and 82.1% of patients without ischemic heart disease this difference was not statistically significant p value was 0.716. Hypertension was present in 72.5% of patients with ischemic heart disease and 27.5% of patients with ischemic heart disease had no hypertension, while 82.5% of patients without ischemic heart disease had hypertension and 17.5% had no hypertension nor ischemic heart disease, this difference was not statistically significant p value = 0.241.

Recommendation: Increased awareness of post-stroke seizures may be important in improving outcomes following the stroke. Further research is needed as a cohort study to know more information about post-stroke seizures.

 Keywords: Seizure; Post-Stroke; Benghazi

References

1. Langhorne P., et al. “Medical complications after stroke: a multicenter study.” Stroke6 (2000): 1223-1229.
2. Myint PK., et al. “Post-stroke seizure, and post- stroke epilepsy”. Postgraduate Medical Journal 971 (2006): 568-572.
3. Kramer G. “Epilepsy in the elderly: some clinical and pharmacotherapeutic aspects”. Epilepsia (2001): 4255-4259.
4. Wallce H., et al. “Age‐specific incidence and prevalence rates of treated epilepsy in an unselected population of 2,052,922 and age‐specific fertility rates of women with epilepsy”. Lancet 352 (1998): 1970-1973.
5. Bladin CF., et al. “Seizures After Stroke: A Prospective Multicenter Study”. Archives of Neurology 11 (2000): 1617-1622.
6. Michael Y Xu. “Poststroke seizure: optimizing its management”. Stroke and Vascular Neurology 4 (2019): e000175.
7. Koubeissi Mohamad. “Seizures worsen stroke outcome: new evidence from a large sample”. Epilepsy Currents1 (2015): 30-31.
8. Camilo Osvaldo and Larry B Goldstein. “Seizures and epilepsy after ischemic stroke”. Stroke7 (2004): 1769-1775.
9. Carolina Ferreira-Atuesta., et al. “Seizures after Ischemic Stroke: A Matched Multicenter Study”. Annals-of-Neurology5 (2021): 808-820.
10. Sitian Ma., et al. “Risk factors for early-onset seizures after stroke: A systematic review and meta-analysis of 18 observational studies”. Brain-and- Behavior6 (2021): e02142.
11. Wang G., et al. “Analysis of risk factors for first seizure after stroke in Chinese patients”. BioMed Research International (2013): 702871.
12. Lin Ru., et al. “Risk of Post-stroke Epilepsy Following Stroke-Associated Acute Symptomatic Seizures”. Frontiers in Aging Neuroscience 13 (2021): 707732.
13. C-Y Sung and N-S Chu. “Epileptic seizures in intracerebral haemorrhage”. Journal of Neurology Neurosurgery and Psychiatry11 (1989): 1273-1276.
14. AN Pinto., et al. “Seizures at the onset of subarachnoid haemorrhage”. Journal of Neurology2 (1996): 161-164.
15. H Butzkueven., et al. “Onset seizures independently predict poor outcome after subarachnoid hemorrhage”. Neurology9 (2000): 1315-1320.
16. Tanaka T., et al. “Seizure Outcomes and Predictors of Recurrent Post-Stroke Seizure: A Retrospective Observational Cohort Study”. PLoS One8 (2015): e0136200.

Citation

Citation: Rabha Elsahli and Mohammed FG Elshukri. “Post-Stroke Seizure in Benghazi”. Acta Scientific Neurology 7.3 (2024): 11-20.

Copyright

Copyright: © 2024 Rabha Elsahli and Mohammed FG Elshukri. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.