Zonaid Kabir¹, Momotaj Sohely², Atikur Rahman³, Sayed Maruf Ur Rahman⁵, Ferdous Jahan⁵ and KM Salma⁶

¹Radiologist, National Institute of Kidney Diseases and Urology (NIKDU), Dhaka, Bangladesh
²Lecturer, Department of Community Medicine, Sheikh Hasina Medical College, Tangail, Bangladesh
³Assistant Registrar, Department of Cardiology, National Institute of Cardiovascular Disease and Hospital, Dhaka, Bangladesh
⁴Medical Officer, Department of Urology, Dhaka Medical College Hospital, Dhaka, Bangladesh
⁵Resident, Department of Neonatology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
⁶Radiologist, National Institute of Kidney Diseases and Urology (NIKDU), Dhaka, Bangladesh

*Corresponding Author: Zonaid Kabir, Radiologist, National Institute of Kidney Diseases and Urology (NIKDU), Dhaka, Bangladesh.

Received: November 14, 2023; Published: January 20, 2024

Abstract

Background: Meningiomas are typically benign brain tumors, and their precise characterization is vital for optimal patient management. The comparison between Magnetic Resonance Spectroscopy (MRS) and histopathology in patients with meningioma is a pivotal area of research in the field of neuroimaging and neuropathology.

Aim of the study: The study aimed to compare between magnetic resonance spectroscopy findings and histopathological results in patients with meningioma.

Methods: This was a cross-sectional study conducted at the Department of Radiology & Imaging of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh during the period from October 2019 to September 2021. A total of 45 suspected cases of meningioma were enrolled in this study as the study subjects purposively. For data collection and analysis, MS Office tools and SPSS Version 23.0 were applied. Results: Magnetic Resonance Spectroscopy (MRS) detected 36 positive cases and 7 negative cases of meningioma. Among the 36 MRS-positive cases, 34 were found to be truly positive upon histopathological examination, indicating a high level of accuracy. However, 2 cases were MRS-positive but turned out to be histopathologically negative, signifying false positives. Additionally, out of the 9 MRS-negative cases, 4 were meningiomas upon histopathological evaluation, which were false negatives, while 5 were genuinely negative.

Conclusion: This analysis suggests that magnetic resonance spectroscopy (MRS) demonstrates a strong ability to correctly identify meningiomas when compared to histopathological diagnosis but has a small rate of both false positives and false negatives.

Keywords: Benign; Histopathology; Magnetic Resonance Spectroscopy; Meningioma; Neuropathology; Tumor

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Citation

Citation: Zonaid Kabir., et al. “Comparison Between Magnetic Resonance Spectroscopy and Histopathology in Patients with Meningiomas". Acta Scientific Neurology 7.2 (2024): 29-34.

Copyright

Copyright: © 2024 Zonaid Kabir., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.