Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Research Article Volume 7 Issue 1

Demographic and Clinical Characteristics of Patients with and Without Vascular Dementia Following an Ischemic Stroke

Ivan Barbov1,2,3, Elena Lickova4 and Goce Kalcev3*

1University Clinic of Neurology, Skopje, Republic of North Macedonia
2Faculty of Medicine, St. Cyril and Methodius-Skopje, Skopje, Republic of North Macedonia
3National Alliance for Neuromuscular diseases and Neuroscience, GANGLION Skopje, Skopje, Republic of North Macedonia
4Clinical Public Hospital, Stip, North Macedonia

*Corresponding Author: Goce Kalcev, National Alliance for Neuromuscular diseases and Neuroscience, GANGLION Skopje, Skopje, Republic of North Macedonia.

Received: November 06, 2023; Published: December 02, 2023


Introduction: Vascular dementia (VaD) is one of the most common causes of dementia in the elderly (those over the age of 65), with a variable presentation and unpredictable disease progression. Current evidence indicates that 25-30% of ischemic stroke patients are likely to develop either immediate or delayed vascular cognitive impairment, or VaD. The development of dementia following a stroke is determined by several factors.

Materials and methods: This study involved 100 patients with ischemic stroke, treated and evaluated for 2 years at the University Clinic of Neurology in Skopje, Republic of North Macedonia, divided into two groups: a group of 47 patients who developed vascular dementia after an ischemic stroke (study group) and a group of 53 patients with ischemic stroke who did not develop vascular dementia (control group).

Results: According to the results of this study, the gender and age differences between the two groups are not statistically significant. Also, there is no statistically significant difference between the affected hemisphere and the appearance or absence of vascular dementia during the evaluation period of two years following the ischemic stroke. On the other hand, a statistically significant difference was found when comparing the distribution of patients with a positive diagnosis for clinically relevant stenosis of one or both carotid arteries with the presence of vascular dementia. No statistically significant difference was found between the representation of four of the five factors (arterial hypertension, diabetes type 2, hyperlipidemia, history of tobacco use) and the occurrence or absence of vascular dementia. Contrary to this, the presence of specific cardiovascular diseases highlights an obvious link with the occurrence of vascular dementia.

Conclusions: Monitoring the risk of vascular disease and preventing recurrent strokes are obviously essential for reducing the burden of cognitive decline and vascular dementia.

Keywords: Vascular Dementia; Ischemic Stroke; Vascular Risk Factors; Clinical Investigations; Comorbidities


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Citation: Goce Kalcev., et al. “Demographic and Clinical Characteristics of Patients with and Without Vascular Dementia Following an Ischemic Stroke". Acta Scientific Neurology 7.1 (2024): 03-08.


Copyright: © 2024 Goce Kalcev., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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