Cognitive Dysfunction in Patient with Chronic Medical Condition in Sub-Saharan Africa
Taofiki Ajao Sunmonu*, Adebimpe Funmilola Ogunmodede,
Olubumin Akindele Ogunrin
1Neurology Unit Department of Internal Medicine, Federal Medical Centre Owo,
Nigeria
2Department of Neurology, University Hospitals of North Midlands, NHS Trust,
Stoke on Tent, United Kingdom
*Corresponding Author:Taofiki Ajao Sunmonu, Neurology Unit, Department of
Medicine, Federal Medical Centre, Owo, Ondo state, Nigeria.
Received:
May 18, 2023; Published: July 10, 2023
Abstract
Chronic Medical Condition is a condition that last longer than one year or more, requires ongoing medical attention and limit activities of daily living. Among these conditions in sub-Saharan Africa (SSA) are epilepsy, diabetes mellitus, Human Immunodeficiency Virus infections bronchial asthma, chronic liver disease and others. Cognitive decline could be present in about 60% of patients with chronic medical conditions especially older adults and those with multiple comorbidities. These chronic medical conditions could have heterogenous patterns of presentation and may have different underlying pathophysiological mechanisms. Various instruments used for neuropsychological assessment of cognition in these conditions and treatment is basically through pharmacologic and non-pharmacologic therapies including cognitive behavioural therapy.
This review is an attempt to describe the specific patterns of presentations of cognitive dysfunctions in patients living with common chronic medical conditions in sub-Saharan Africa such as memory, information processing, attention/concentration, learning, visual spatial skills and other executive functions. We also highlighted recent advances of possible pathophysiological mechanism and management of this conditions. Furthermore, well conducted large scale trials to explore the peculiar pathophysiological mechanisms of cognitive decline in patients with chronic medical conditions in sub-Saharan Africa in the near future.
Keywords: Cognition; Cognitive Dysfunctions; Neuropsychology; Chronic Medical Conditions; Africa
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