Shrinkhal*, Pragati Garg, Swarastra Prakash Singh and Ruchi Shukla

Department of Ophthalmology, All India Institute of Medical Sciences, Raebareli, Uttar Pradesh, India

*Corresponding Author: Shrinkhal, Department of Ophthalmology, All India Institute of Medical Sciences, Raebareli, Uttar Pradesh, India.

Received: March 16, 2023; Published: April 01, 2023

Abstract

Giant cell arteritis (GCA) is a systemic disease, characterized by granulomatous inflammation of the large and medium sized arteries. It almost exclusively affects older than 50 years and is part of the spectrum including polymyalgia rheumatica. The incidence of GCA increases with the age. Women are affected more commonly than men. It can lead to profound permanent vision loss, if not detected early due to mainly arteritic anterior ischaemic optic neuropathy. The vision loss can occur within hours to days. If left untreated, around 50% of patients with GCA and vision loss in one eye will lose vision in the opposite eye within 7 days. Treatment is required even if the patient loses vision in the both the eyes, as GCA is a systemic disease.

References

1. Gran JT and Myklebust G. “The incidence of polymyalgia rheumatica and temporal arteritis in the county of Aust Agder, South Norway: a prospective study 1987-1994”. The Journal of Rheumatology 24 (1997): 1739-1743.
2. Martinez-Taboada VM., et al. “Giant cell arteritis with an erythrocyte sediemtation rate lower than 50”. Clinical Rheumatology 19 (2000): 73-75.
3. Salvarani C and Hunder GG. “Giant cell arteritis with low erythrocyte sedimentation rate: frequency of occurrence in a population-based study”. Arthritis and Rheumatology 45 (2001): 140-145.
4. Evans JM., et al. “Increased incidence of aortic aneuysm and dissection in giant cell (temporal) arteritis. A population based study”. Annals of Internal Medicine 122 (1995): 502-507.
5. Lie JT. “Aortic and extracranial large vessel giant cell arteritis. A review of 72 cases with histopathological documentation”. Seminars in Arthritis and Rheumatism 24 (1995): 422-431.

Citation

Citation: Shrinkhal., et al. “Giant Cell Arteritis: A Clinical Challenge". Acta Scientific Neurology 6.5 (2023): 01-02.

Copyright

Copyright: © 2023 Shrinkhal., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.