Acta Scientific Neurology (ASNE) (ISSN: 2582-1121)

Research Article Volume 6 Issue 3

Prevalence of Epilepsy in Rural Areas of Madagascar

Rahamefy Odilon Randrianasolo1*, Glorien Lemahafaka2, Dorée Augustia Raharimaminjatovosoa3, Julien Razafimahefa4, Noel Zodaly4 and Alain Djacoba Tehindrazanarivelo4

1Neurology Department, PZAGA University Hospital, Faculty of Medicine, University of Majunga, Madagascar
2Neurology Department, Tanambao University Hospital, Faculty of Medicine, University of Toliary, Madagascar
3Neurology Department, Place Kabary University Hospital, Faculty of Medicine, University of Antsiranana, Madagascar
4Neurology Department, Befelatanana University Hospital, Faculty of Medicine, University of Antananarivo, Madagascar

*Corresponding Author: Rahamefy Odilon Randrianasolo, Neurology Department, PZAGA University Hospital, Faculty of Medicine, University of Majunga, Madagascar.

Received: February 05, 2023; Published: February 22, 2023

Abstract

To estimate the prevalence of epilepsy in the rural community of the western province of Madagascar, a door-to-door survey of the general population was carried out in the rural community of Ambolomoty in the Western province of Madagascar during September and October 2021. Cluster sampling was used with a cluster effect of 3, an expected prevalence of 5%, and a 95% confidence interval. Face-to-face interviews by trained investigator, were conducted using a structured questionnaire. Epilepsy was defined as the occurrence of at least two seizures. Two hundred and forty-one subjects were investigated. The crude prevalence of epilepsy was 9.2%. Epilepsy begins before the age of five years in 81.81%. Structural epilepsy was found in 86.36%, and motor generalized onset in 81.81%. A history of obstructed labor was reported in 59.09% with resuscitation at birth for all. In this rural community, the occurrence of epilepsy was four times higher than in other localities of Madagascar. The high frequency of birth injuries and severe structural epilepsy could be one of the causes of this situation. The reinforced strategy of epilepsy management and improved birth injury prevention should be implemented in an emergency in this locality.

Keywords:Prevalence; General Population; Birth Injuries; Developmental Disorders; Madagascar

References

  1. Fisher RS., et al. “ILAE official report: a practical clinical definition of epilepsy”. Epilepsia 4 (2014): 47582.
  2. “Principaux repères sur l’épilepsie.
  3. Ba-Diop A., et al. “Epidemiology, causes, and treatment of epilepsy in sub-Saharan Africa”. Lancet Neurology10 (2014): 102944.
  4. Raolisaona Mamitiana., et al. “Facteurs de risques d’épilepsie dans le village central de la SIRAMA Ambilobe”. Thèse, Faculté de Médecine d'Antananarivo (2002).
  5. Andriantseheno LM and Ralaizandriny D. “Prévalence communautaire de l’épilepsie chez les Malgaches”. Epilepsies2 (2004): 836.
  6. Preux PM., et al. “Questionnaire d’Investigation de l’Épilepsie dans les Pays Tropicaux (Francais)”. African Journal of Neurological Sciences (2021): 21.
  7. Feigin VL., et al. “Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016”. Lancet Neurology5 (2019): 45980.
  8. Beghi E., et al. “Global, regional, and national burden of epilepsy, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016”. Lancet Neurology4 (2019): 357‑375.
  9. INSTAT Madagascar. Monographie de la commune d’Ambolomoty sous/préfecture de Marovoay.
  10. Bony KE., et al. “Profil épidémiologique, clinique et thérapeutique des épilepsies a Bouake (Côte d’Ivoire)”. African Journal of Neurological Sciences 1 (2020): 611.
  11. Prischich F., et al. “High prevalence of epilepsy in a village in the Littoral Province of Cameroon”. Epilepsy Research23 (2008): 20010.
  12. Yemadje LP., et al. “Understanding the differences in prevalence of epilepsy in tropical regions”. Epilepsia8 (2011): 137681.
  13. Sun Y., et al. “Apgar Scores and Long-Term Risk of Epilepsy”. Epidemiology3 (2006): 296301.
  14. Persson M., et al. “Five and 10 minutes Apgar scores and risks of cerebral palsy and epilepsy: population based cohort study in Sweden”. BMJ 360 (2018): k207.
  15. Andriantsimahavandy A., et al. “Neurocysticercosis: a major aetiological factor of late-onset epilepsy in Madagascar”. Tropical Medicine and International Health: TM and IH 8 (1997): 7416.
  16. Gripper LB and Welburn SC. “The causal relationship between neurocysticercosis infection and the development of epilepsy - a systematic review”. Infectious Diseases of Poverty 6 (2017): 31.

Citation

Citation: Rahamefy Odilon Randrianasolo., et al. “Prevalence of Epilepsy in Rural Areas of Madagascar". Acta Scientific Neurology 6.3 (2023): 29-33.

Copyright

Copyright: © 2023 Rahamefy Odilon Randrianasolo., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate32%
Acceptance to publication20-30 days

Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 10, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US