Post-Stroke Epilepsy : Epidemiological, Electro-Clinical and Therapeutic Aspects at the Loandjili General Hospital in Pointe-Noire, Republic of Congo
Ngassaki SR1*, Sounga PEG1,2, Bakoudissa RW1, Ndotabeka LJ1, Detsele RC1, Mialoundama C1, ITOUA G J S, Oko-Lossambo C1 and Koubemba C G1
1Department of Neurology, Loandjili General Hospital, Pointe-Noire, Republic of Congo
2Marien NGOUABI University, Faculty of Health Sciences, Republic of Congo
*Corresponding Author: Ngassaki SR, Department of Neurology, Loandjili General Hospital, Pointe-Noire, Republic of Congo.
November 04, 2022; Published: December 08, 2022
Introduction: Post-stroke epilepsy is the leading cause of epilepsy in the elderly. The diagnosis can be difficult in case of non-convulsive manifestations. So-called novel anti-epileptic drugs are more appropriate as low-dose monotherapy. The purpose of this study was to determine the epidemiological, electro-clinical and therapeutic aspects of post-stroke epilepsy in our practice.
Patients and methods: We conducted a cross-sectional study with a descriptive and analytical aim over a period of 12 months. We interviewed, reviewed and consulted records of inpatients during the study period. Chi2, t-student and Anova tests were used for the comparison of variables.
Results: 583 patients were collected. Among them, 46 suffered from Post-stroke epilepsy with a hospital frequency of 7.89%. This epilepsy occurred mostly a year after stroke and predominated in men. It mainly complicated ischemic stroke (95.7%) and manifested itself mainly in the form of generalized tonic-clonic seizures. Status epilepticus was common and was not associated with mortality. Ancient anti-epileptic drugs especially phenobarbital were used with excellent therapeutic success as low-dose monotherapy. Our patients were mostly hypertensive.
Conclusion: Post-stroke epilepsy is common and of favorable course under antiepileptic drugs. Secondary prevention of hypertension and stroke would reduce the risk of post-stroke epilepsy.
Keywords: Epilepsy; Vascular; Pointe-Noire; Congo
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